Stadium: Highmark Stadium Round: 3
Home Manager: Zac Taylor Away Manager: Sean McDermott
| 1 | 2 | H | 3 | 4 | F |
|---|---|---|---|---|---|
| 0 | 0 | 0 | 7 | 10 | 17 |
| 8 | 6 | 14 | 0 | 7 | 21 |
| Holden/Barlow/Martin | BUF Bills |
| Lineup | |
|---|---|
| 30 - SAF - Jessie Bates | Isaiah McKenzie - WR - 19 |
| 53 - Center - Billy Price | Dean Marlowe - SAF - 31 |
| 57 - Left back - Germaine Pratt | Jon Feliciano - OG - 76 |
| 91 - DT - Josh Tupou | Tremaine Edmunds - Left back - 49 |
| 15 - WR - Damion Willis | Robert Foster - WR - 16 |
| 82 - TE - Cethan Carter | Mitch Morse - Center - 60 |
| 74 - OG - Keaton Sutherland | Jordan Phillips - DE - 97 |
| 32 - Right back - Trayveon Williams | T.J. Yeldon - Right back - 22 |
| 19 - WR - Auden Tate | Kevin Johnson - Center back - 29 |
| 94 - DE - Sam Hubbard | Kurt Coleman - SS - 28 |
| 93 - DT - Andrew Brown | Levi Wallace - Center back - 39 |
| 89 - TE - Drew Sample | Spencer Long - OL - 61 |
| 5 - QB - Ryan Finley | Quinton Spain - OG - 67 |
| 24 - Center back - Darius Phillips | Josh Allen - QB - 17 |
| 95 - DT - Renell Wren | Matt Milano - Left back - 58 |
| 50 - Left back - Jordan Evans | Harrison Phillips - DT - 99 |
| 58 - DE - Carl Lawson | Dion Dawkins - OT - 73 |
| 67 - OG - John Miller | Siran Neal - Center back - 33 |
| 36 - SAF - Shawn Williams | Corey Thompson - Left back - 52 |
| 71 - OT - Andre Smith | Darryl Johnson - DE - 92 |
| 14 - QB - Andy Dalton | Reid Ferguson - LS - 69 |
| 85 - TE - Tyler Eifert | Tre'Davious White - Center back - 27 |
| 55 - OLB - LaRoy Reynolds | Corey Bojorquez - Pivot - 9 |
| 4 - K - Randy Bullock | Shaq Lawson - DE - 90 |
| 10 - Pivot - Kevin Huber | Maurice Alexander - OLB - 41 |
| 64 - OG - John Jerry | Trent Murphy - DE - 93 |
| 52 - MLB - Preston Brown | Andre Roberts - WR - 18 |
| 97 - DT - Geno Atkins | Cody Ford - OL - 70 |
| 27 - Center back - Dre Kirkpatrick | Ed Oliver - DT - 91 |
| 25 - Right back - Giovani Bernard | Zay Jones - WR - 11 |
| 87 - TE - C.J. Uzomah | Jordan Poyer - SAF - 21 |
| 68 - OT - Bobby Hart | Jerry Hughes - DE - 55 |
| 40 - SAF - Brandon Wilson | Matt Barkley - QB - 5 |
| 34 - Right back - Samaje Perine | Dawson Knox - TE - 88 |
| 99 - DT - Andrew Billings | Cole Beasley - WR - 10 |
| 28 - Right back - Joe Mixon | Tommy Sweeney - TE - 89 |
| 11 - WR - John Ross | Patrick DiMarco - FB - 42 |
| 29 - Center back - Tony McRae | Lorenzo Alexander - OLB - 57 |
| 22 - Center back - William Jackson | Ty Nsekhe - OT - 77 |
| 59 - Left back - Nick Vigil | John Brown - WR - 15 |
| 12 - WR - Alex Erickson | Steven Hauschka - K - 4 |
| 42 - SS - Clayton Fejedelem | Frank Gore - Right back - 20 |
| 96 - DE - Carlos Dunlap | Star Lotulelei - DT - 98 |
| 83 - WR - Tyler Boyd | Lee Smith - TE - 85 |
| 66 - Center - Trey Hopkins | Micah Hyde - SAF - 23 |
| 46 - LS - Clark Harris | Julian Stanford - Left back - 51 |
| Substitutes | |