Head to Head
| England FA WSL 2 | 2025/11/16 12:00 | Southampton (W) v Durham (W) | D | 1-1 |
| England Championship Women | 2025/01/26 12:00 | Durham (W) v Southampton (W) | W | 1-0 |
| England Championship Women | 2024/11/10 12:00 | Southampton (W) v Durham (W) | D | 1-1 |
| England Championship Women | 2023/12/17 12:00 | Durham (W) v Southampton (W) | W | 1-0 |
| England Championship Women | 2023/10/15 11:00 | Southampton (W) v Durham (W) | L | 2-1 |
| England Championship Women | 2023/03/19 12:00 | Southampton (W) v Durham (W) | W | 0-1 |
| England Championship Women | 2023/01/22 12:00 | Durham (W) v Southampton (W) | D | 0-0 |
Home History
| England FA National League Cup Women | 2025/11/23 14:00 | Sunderland (W) v Durham (W) | D | 1-1 |
| England FA WSL 2 | 2025/11/16 12:00 | Southampton (W) v Durham (W) | D | 1-1 |
| England FA WSL 2 | 2025/11/09 12:00 | Durham (W) v Newcastle (W) | D | 1-1 |
| England FA WSL 2 | 2025/11/02 13:00 | Sheff Utd (W) v Durham (W) | L | 2-1 |
| England League Cup Women | 2025/10/16 18:00 | Durham (W) v Liverpool (W) | L | 1-2 |
| England FA WSL 2 | 2025/10/12 11:00 | Durham (W) v Nottm Forest (W) | W | 3-0 |
| England FA WSL 2 | 2025/10/05 13:00 | Bristol City (W) v Durham (W) | L | 2-1 |
| England FA WSL 2 | 2025/09/28 11:00 | Durham (W) v Crystal Palace (W) | D | 1-1 |
Away History
| England FA National League Cup Women | 2025/11/23 14:00 | Southampton (W) v Charlton (W) | L | 1-2 |
| England FA WSL 2 | 2025/11/16 12:00 | Southampton (W) v Durham (W) | D | 1-1 |
| England League Cup Women | 2025/11/12 19:00 | West Ham (W) v Southampton (W) | L | 5-0 |
| England FA WSL 2 | 2025/11/09 14:00 | Charlton (W) v Southampton (W) | L | 2-1 |
| England FA WSL 2 | 2025/11/02 14:00 | Southampton (W) v Nottm Forest (W) | L | 2-3 |
| England League Cup Women | 2025/10/19 13:00 | Brighton (W) v Southampton (W) | L | 3-0 |
| England FA WSL 2 | 2025/10/12 13:00 | Portsmouth (W) v Southampton (W) | W | 2-5 |
| England League Cup Women | 2025/10/08 18:00 | Southampton (W) v Portsmouth (W) | W | 1-0 |