Stadium: Estadio Parque del Guaira Round: 26
| Paraguay Division Intermedia | 2025/06/02 22:00 | Deportivo Santaní v Guairena FC | W | 0-2 |
| Paraguay Division Intermedia | 2024/09/28 14:00 | Deportivo Santaní v Guairena FC | D | 2-2 |
| Paraguay Division Intermedia | 2024/06/21 21:00 | Guairena FC v Deportivo Santaní | D | 1-1 |
| Paraguay Division Intermedia | 2017/07/30 19:00 | Deportivo Santaní v Guairena FC | W | 0-1 |
| Paraguay Division Intermedia | 2017/04/23 19:00 | Guairena FC v Deportivo Santaní | D | 1-1 |
| Paraguay Division Intermedia | 2025/06/22 21:30 | Guairena FC v River Plate Asuncion | L | 0-1 |
| Paraguay Division Intermedia | 2025/06/15 21:30 | Rubio Nu v Guairena FC | L | 2-1 |
| Paraguay Division Intermedia | 2025/06/06 22:15 | Guairena FC v Pastoreo FC | D | 1-1 |
| Paraguay Division Intermedia | 2025/06/02 22:00 | Deportivo Santaní v Guairena FC | W | 0-2 |
| Paraguay Division Intermedia | 2025/05/26 22:00 | Guairena FC v Tacuary | W | 1-0 |
| Paraguay Division Intermedia | 2025/05/19 20:00 | Resistencia FC v Guairena FC | L | 1-0 |
| Paraguay Division Intermedia | 2025/05/13 13:00 | Guairena FC v Sportivo San Lorenzo | L | 0-2 |
| Paraguay Division Intermedia | 2025/05/08 22:30 | Guairena FC v Carapegua | D | 1-1 |
| Paraguay Division Intermedia | 2025/06/21 18:00 | Deportivo Santaní v Sportivo San Lorenzo | L | 0-1 |
| Paraguay Division Intermedia | 2025/06/13 18:30 | Deportivo Santaní v Tacuary | L | 0-1 |
| Paraguay Division Intermedia | 2025/06/09 20:00 | Resistencia FC v Deportivo Santaní | D | 3-3 |
| Paraguay Division Intermedia | 2025/06/02 22:00 | Deportivo Santaní v Guairena FC | L | 0-2 |
| Paraguay Division Intermedia | 2025/05/25 13:00 | Carapegua v Deportivo Santaní | L | 4-0 |
| Paraguay Division Intermedia | 2025/05/20 20:00 | Deportivo Santaní v Independiente FBC | W | 2-1 |
| Paraguay Division Intermedia | 2025/05/16 13:00 | Sol de America v Deportivo Santaní | L | 2-1 |
| Paraguay Division Intermedia | 2025/05/11 13:00 | Deportivo Santaní v Fernando de la Mora | W | 2-0 |