Southern Illinois 26-44 SE Missouri St 2019-05-15 17:30
Stadium: Houck Stadium Round: 1
Home Manager: Nick Hill Away Manager: Tom Matukewicz
Head to Head
| NCAAF | 2018/09/15 23:00 | SE Missouri St v SO Illinois | L | 48-44 |
| NCAAF | 2017/09/16 23:00 | SE Missouri St v SO Illinois | W | 17-35 |
Home History
| NCAAF FCS | 2018/11/17 20:30 | SO Illinois v North Dakota State | L | 17-65 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | L | 57-38 |
| NCAAF FCS | 2018/11/03 18:00 | Western Illinois v SO Illinois | L | 34-31 |
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | W | 35-49 |
| NCAAF | 2018/10/20 19:00 | SO Illinois v Indiana State | L | 21-24 |
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | L | 3-51 |
| NCAAF | 2018/10/06 22:00 | SO Illinois v Youngstown State | L | 14-17 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
Away History
| NCAAF FCS | 2018/12/01 21:00 | SE Missouri St v Weber State | L | 23-48 |
| NCAAF FCS | 2018/11/24 19:00 | Stony Brook v SE Missouri St | W | 14-28 |
| NCAAF FCS | 2018/11/17 19:00 | Eastern Illinois v SE Missouri St | W | 32-38 |
| NCAAF FCS | 2018/11/10 17:00 | SE Missouri St v Murray State | L | 38-40 |
| NCAAF FCS | 2018/11/03 18:00 | Tennessee State v SE Missouri St | W | 21-38 |
| NCAAF | 2018/10/27 19:00 | Tennessee Martin v SE Missouri St | W | 33-56 |
| NCAAF | 2018/10/20 18:00 | SE Missouri St v Jacksonville State | W | 37-14 |
| NCAAF | 2018/10/13 18:00 | Austin Peay v SE Missouri St | W | 27-31 |