Head to Head
| NCAAF | 2010/10/30 12:00 | Iowa v Michigan State | W | 37-6 |
| NCAAF | 2009/10/24 12:00 | Michigan State v Iowa | W | 13-15 |
| NCAAF | 2008/10/04 12:00 | Michigan State v Iowa | L | 16-13 |
| NCAAF | 2007/10/27 12:00 | Iowa v Michigan State | W | 34-27 |
| NCAAF | 2004/10/02 12:00 | Iowa v Michigan State | W | 38-16 |
| NCAAF | 2003/09/27 12:00 | Michigan State v Iowa | L | 20-10 |
| NCAAF | 2002/10/12 12:00 | Iowa v Michigan State | W | 44-16 |
| NCAAF | 2001/10/13 12:00 | Michigan State v Iowa | L | 31-28 |
Home History
| NCAAF | 2010/11/27 12:00 | Minnesota v Iowa | L | 27-24 |
| NCAAF | 2010/11/20 12:00 | Iowa v Ohio State | L | 17-20 |
| NCAAF | 2010/11/13 12:00 | Northwestern v Iowa | L | 21-17 |
| NCAAF | 2010/11/06 12:00 | Indiana v Iowa | W | 13-18 |
| NCAAF | 2010/10/30 12:00 | Iowa v Michigan State | W | 37-6 |
| NCAAF | 2010/10/23 12:00 | Iowa v Wisconsin | L | 30-31 |
| NCAAF | 2010/10/16 12:00 | Michigan v Iowa | W | 28-38 |
| NCAAF | 2010/10/02 12:00 | Iowa v Penn State | W | 24-3 |
Away History
| NCAAF | 2010/11/27 12:00 | Penn State v Michigan State | W | 22-28 |
| NCAAF | 2010/11/20 12:00 | Michigan State v Purdue | W | 35-31 |
| NCAAF | 2010/11/06 12:00 | Michigan State v Minnesota | W | 31-8 |
| NCAAF | 2010/10/30 12:00 | Iowa v Michigan State | L | 37-6 |
| NCAAF | 2010/10/23 12:00 | Northwestern v Michigan State | W | 27-35 |
| NCAAF | 2010/10/16 12:00 | Michigan State v Illinois | W | 26-6 |
| NCAAF | 2010/10/09 12:00 | Michigan v Michigan State | W | 17-34 |
| NCAAF | 2010/10/02 12:00 | Michigan State v Wisconsin | W | 34-24 |