Stadium: Harms-Eischeid Stadium Round: 1
| NCAAF | 2018/11/10 18:00 | Minnesota State Mankato Mavericks v Upper Iowa | L | 47-7 |
| NCAAF | 2018/11/03 17:05 | Upper Iowa v Wayne State Wildcats | L | 35-42 |
| NCAAF | 2018/10/27 18:00 | Sioux Falls Cougars v Upper Iowa | L | 34-7 |
| NCAAF | 2018/10/20 19:00 | St Cloud State Huskies v Upper Iowa | L | 34-14 |
| NCAAF | 2018/10/13 19:05 | Upper Iowa v Bemidji State Beavers | W | 27-24 |
| NCAAF | 2018/10/06 18:00 | Minot State Beavers v Upper Iowa | W | 9-44 |
| NCAAF | 2018/09/29 20:05 | Upper Iowa v Minnesota State University Moorhead Dragons | L | 13-17 |
| NCAAF | 2018/09/22 18:00 | Southwest Minnesota State Mustangs v Upper Iowa | L | 21-20 |
| NCAAF | 2018/11/10 19:00 | Southwest Minnesota State Mustangs v Augustana Vikings | L | 18-28 |
| NCAAF | 2018/11/03 18:00 | Southwest Minnesota State Mustangs v Concordia University Golden Bears | L | 10-16 |
| NCAAF | 2018/10/27 18:00 | Winona State Warriors v Southwest Minnesota State Mustangs | L | 38-26 |
| NCAAF | 2018/10/20 22:00 | Southwest Minnesota State Mustangs v Northern State Wolves | W | 35-7 |
| NCAAF | 2018/10/13 18:05 | Minnesota Duluth Bulldogs v Southwest Minnesota State Mustangs | L | 42-13 |
| NCAAF | 2018/10/06 22:00 | Southwest Minnesota State Mustangs v Minnesota Crookston Golden Eagles | W | 55-6 |
| NCAAF | 2018/09/29 19:00 | University of Mary Marauders v Southwest Minnesota State Mustangs | W | 24-54 |
| NCAAF | 2018/09/22 18:00 | Southwest Minnesota State Mustangs v Upper Iowa | W | 21-20 |