[5] Santos Laguna 1-4 Toluca [4] 2016-12-21 16:30
Weather: Good Stadium: Estadio TSM Corona Pitch: Good Round: 3
Referee: Paul Enrique Delgadillo Haro Home Manager: Jose Manuel De la Torre Away Manager: Hernan Cristante
Head to Head
| Mexico Liga MX | 2016/11/20 18:00 | Toluca v Santos Laguna | W | 1-2 |
| Mexico Liga MX | 2016/04/02 02:30 | Toluca v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2015/10/04 00:00 | Santos Laguna v Toluca | D | 0-0 |
| Mexico Liga MX | 2015/02/15 18:00 | Toluca v Santos Laguna | D | 2-2 |
| Mexico Liga MX | 2014/08/23 02:30 | Santos Laguna v Toluca | W | 3-0 |
Home History
| Mexico Liga MX | 2016/11/20 18:00 | Toluca v Santos Laguna | W | 1-2 |
| Mexico Liga MX | 2016/11/07 00:00 | Santos Laguna v Jaguares de Chiapas FC | W | 2-0 |
| Mexico Liga MX | 2016/10/30 02:00 | Club America v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2016/10/23 23:00 | Santos Laguna v Atlas | D | 2-2 |
| Mexico Liga MX | 2016/10/16 00:06 | Pachuca v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2016/10/01 22:00 | Queretaro v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2016/09/25 23:00 | Santos Laguna v Tijuana | L | 1-2 |
| Mexico Liga MX | 2016/09/22 02:30 | Monterrey v Santos Laguna | L | 5-2 |
Away History
| Mexico Liga MX | 2016/11/20 18:00 | Toluca v Santos Laguna | L | 1-2 |
| Mexico Liga MX | 2016/11/05 23:00 | Queretaro v Toluca | W | 2-3 |
| Mexico Liga MX | 2016/10/30 18:00 | Toluca v Tijuana | L | 0-1 |
| Mexico Cup | 2016/10/26 02:00 | Toluca v Queretaro | L | 7-8 |
| Mexico Liga MX | 2016/10/23 00:00 | Monterrey v Toluca | D | 1-1 |
| Mexico Cup | 2016/10/20 02:00 | Puebla v Toluca | W | 0-2 |
| Mexico Liga MX | 2016/10/16 17:00 | Toluca v Unam Pumas | W | 2-1 |
| Mexico Liga MX | 2016/10/02 02:00 | Necaxa v Toluca | L | 3-1 |