[5] Northampton 17-14 Sale Sharks [4] 2021-02-22 20:45
Stadium: Franklin's Gardens Round: 13
Referee: Matthew Carley Home Manager: Chris Boyd Away Manager: Paul Deacon
Head to Head
| Prem Rugby | 2020/11/20 20:00 | Sale Sharks v Northampton | L | 32-23 |
| Prem Rugby | 2020/09/29 16:30 | Northampton v Sale Sharks | L | 14-34 |
| Prem Rugby | 2019/12/21 15:00 | Sale Sharks v Northampton | L | 22-10 |
| Premier Rugby Cup | 2019/09/21 14:00 | Sale Sharks v Northampton | L | 39-18 |
| Prem Rugby | 2019/02/16 14:00 | Northampton v Sale Sharks | W | 67-17 |
| Prem Rugby | 2018/11/24 13:00 | Sale Sharks v Northampton | L | 18-13 |
| Prem Rugby | 2018/03/03 15:00 | Northampton v Sale Sharks | L | 25-34 |
| LV Cup | 2018/01/27 14:00 | Sale Sharks v Northampton | W | 20-24 |
Home History
| Prem Rugby | 2021/02/20 15:00 | Exeter Chiefs v Northampton | W | 12-13 |
| Prem Rugby | 2021/02/06 13:00 | Wasps v Northampton | W | 17-22 |
| Prem Rugby | 2021/01/30 15:00 | Gloucester v Northampton | W | 26-31 |
| Prem Rugby | 2020/12/26 16:30 | Northampton v Worcester Warriors | W | 29-10 |
| European Rugby Champions Cup | 2020/12/19 13:00 | Leinster v Northampton | L | 35-19 |
| European Rugby Champions Cup | 2020/12/11 17:30 | Northampton v Bordeaux | L | 12-16 |
| Prem Rugby | 2020/12/04 19:45 | Bristol v Northampton | L | 18-17 |
| Prem Rugby | 2020/11/28 14:00 | Northampton v Harlequins | L | 29-49 |
Away History
| Prem Rugby | 2021/02/20 13:00 | Harlequins v Sale Sharks | L | 24-12 |
| Prem Rugby | 2021/02/12 20:00 | Sale Sharks v Bath | L | 22-27 |
| Prem Rugby | 2021/02/05 19:45 | Bristol v Sale Sharks | W | 13-20 |
| Prem Rugby | 2021/01/29 19:45 | Leicester v Sale Sharks | W | 15-25 |
| Prem Rugby | 2021/01/08 20:00 | Sale Sharks v Worcester Warriors | W | 20-13 |
| Prem Rugby | 2021/01/02 16:30 | Gloucester v Sale Sharks | W | 19-22 |
| Prem Rugby | 2020/12/27 15:00 | Sale Sharks v Wasps | L | 23-26 |
| European Rugby Champions Cup | 2020/12/19 20:00 | Sale Sharks v Edinburgh | L | 15-16 |