Stadium: The William Exum Center Round: 2
Home Manager: Heather Vulin Away Manager: Kate Achter
| WNCAAB | 2021/01/10 22:00 | Manhattan (W) v Marist (W) | L | 46-50 |
| WNCAAB | 2021/01/09 22:00 | Marist (W) v Manhattan (W) | L | 52-44 |
| WNCAAB | 2021/01/02 23:00 | Manhattan (W) v St. Peter's (W) | W | 69-55 |
| WNCAAB | 2021/01/01 23:00 | Manhattan (W) v St. Peter's (W) | W | 71-46 |
| WNCAAB | 2020/12/23 17:00 | Manhattan (W) v Rutgers (W) | L | 41-84 |
| WNCAAB | 2020/12/20 00:00 | Manhattan (W) v Quinnipiac (W) | L | 50-61 |
| WNCAAB | 2020/12/18 23:00 | Manhattan (W) v Quinnipiac (W) | W | 71-70 |
| WNCAAB | 2020/12/13 00:00 | Rider Women v Manhattan (W) | W | 38-50 |
| WNCAAB | 2021/01/02 19:00 | Indiana State (W) v Loyola Chicago (W) | W | 52-59 |
| WNCAAB | 2021/01/01 18:00 | Indiana State (W) v Loyola Chicago (W) | L | 63-48 |
| WNCAAB | 2020/12/21 18:00 | Loyola Chicago (W) v Central Michigan (W) | L | 64-73 |
| WNCAAB | 2020/12/19 01:00 | Loyola Chicago (W) v Purdue Northwest Women | W | 80-61 |
| WNCAAB | 2020/12/13 21:00 | DePaul (W) v Loyola Chicago (W) | L | 76-67 |
| WNCAAB | 2020/11/28 19:00 | Chicago State (W) v Loyola Chicago (W) | W | 57-70 |
| WNCAAB | 2020/03/07 20:00 | Loyola Chicago (W) v Missouri State (W) | L | 61-72 |
| WNCAAB | 2020/03/06 00:00 | Southern Illinois (W) v Loyola Chicago (W) | L | 58-41 |