[53] Kei Nishikori 6-4,6-4,6-4 Alexei Popyrin [67] 2021-06-10 20:00
Stadium: Court 17 Round: 23 Ground: Grass
Home History
| French Open | 2021/06/06 19:00 | Alexander Zverev v Kei Nishikori | 6-4,6-1,6-1 |
| French Open | 2021/06/02 11:15 | Karen Khachanov v Kei Nishikori | 6-4,2-6,6-2,4-6,4-6 |
| French Open | 2021/05/30 12:30 | Kei Nishikori v Alessandro Giannessi | 6-4,6-7,6-3,4-6,6-4 |
| ATP Rome | 2021/05/13 15:05 | Alexander Zverev v Kei Nishikori | 4-6,6-3,6-4 |
| ATP Rome | 2021/05/10 09:35 | Kei Nishikori v Fabio Fognini | 6-3,6-4 |
| ATP Madrid | 2021/05/05 11:05 | Kei Nishikori v Alexander Zverev | 3-6,2-6 |
| ATP Madrid | 2021/05/04 09:00 | Karen Khachanov v Kei Nishikori | 7-6,2-6,2-6 |
| ATP Barcelona | 2021/04/22 14:00 | Rafael Nadal v Kei Nishikori | 6-0,2-6,6-2 |
Away History
| ATP Stuttgart | 2021/06/09 17:10 | Feliciano Lopez v Alexei Popyrin | 6-4,6-4 |
| French Open | 2021/06/01 14:00 | Rafael Nadal v Alexei Popyrin | 6-3,6-2,7-6 |
| ATP Rome | 2021/05/08 15:40 | Kamil Majchrzak v Alexei Popyrin | 7-6,6-7,6-3 |
| ATP Madrid | 2021/05/06 13:00 | Rafael Nadal v Alexei Popyrin | 6-3,6-3 |
| ATP Madrid | 2021/05/05 14:00 | Alexei Popyrin v Jannik Sinner | 7-6,6-2 |
| ATP Madrid | 2021/05/04 11:35 | Alexei Popyrin v Jan-Lennard Struff | 6-3,7-6 |
| ATP Madrid | 2021/05/02 11:25 | Arthur Cazaux v Alexei Popyrin | 5-7,6-7 |
| ATP Madrid | 2021/05/01 14:25 | Federico Coria v Alexei Popyrin | 7-6,4-6,3-6 |