[7] Barcelona 0-1 Real Betis [5] 2021-09-14 19:15
Stadium: Camp Nou Round: 16
Referee: Pablo Gonzalez Fuertes Home Manager: Xavi Away Manager: Manuel Pellegrini
Head to Head
| Spain La Liga | 2021/02/07 20:00 | Real Betis v Barcelona | W | 2-3 |
| Spain La Liga | 2020/11/07 15:15 | Barcelona v Real Betis | W | 5-2 |
| Spain La Liga | 2020/02/09 20:00 | Real Betis v Barcelona | W | 2-3 |
| Spain La Liga | 2019/08/25 19:00 | Barcelona v Real Betis | W | 5-2 |
| Spain La Liga | 2019/03/17 19:45 | Real Betis v Barcelona | W | 1-4 |
| Spain La Liga | 2018/11/11 15:15 | Barcelona v Real Betis | L | 3-4 |
| Spain La Liga | 2018/01/21 19:45 | Real Betis v Barcelona | W | 0-5 |
| Spain La Liga | 2017/08/20 18:15 | Barcelona v Real Betis | W | 2-0 |
Home History
| UEFA Champions League | 2021/09/14 19:00 | Barcelona v Bayern Munich | L | 0-3 |
| Spain La Liga | 2021/08/29 15:00 | Barcelona v Getafe | W | 2-1 |
| Spain La Liga | 2021/08/21 20:00 | Athletic Bilbao v Barcelona | D | 1-1 |
| Spain La Liga | 2021/08/15 18:00 | Barcelona v Real Sociedad | W | 4-2 |
| Elite Club Friendlies | 2021/08/08 19:30 | Barcelona v Juventus | W | 3-0 |
| Elite Club Friendlies | 2021/08/04 17:00 | FC Salzburg v Barcelona | L | 2-1 |
| Elite Club Friendlies | 2021/07/31 17:00 | VfB Stuttgart v Barcelona | W | 0-3 |
| Elite Club Friendlies | 2021/07/24 17:00 | Barcelona v Girona | W | 3-1 |
Away History
| Spain La Liga | 2021/09/13 20:00 | Granada v Real Betis | W | 1-2 |
| Spain La Liga | 2021/08/28 20:00 | Real Betis v Real Madrid | L | 0-1 |
| Spain La Liga | 2021/08/20 19:00 | Real Betis v Cadiz | D | 1-1 |
| Spain La Liga | 2021/08/14 17:30 | Mallorca v Real Betis | D | 1-1 |
| Elite Club Friendlies | 2021/08/07 20:00 | Real Betis v Roma | W | 5-2 |
| Europe Friendlies | 2021/08/04 17:00 | Almeria v Real Betis | L | 2-1 |
| Elite Club Friendlies | 2021/07/31 11:30 | Leeds v Real Betis | W | 2-3 |
| Europe Friendlies | 2021/07/28 18:00 | Derby v Real Betis | L | 1-0 |