Head to Head
| England Premier League 2 | 2019/05/13 18:00 | Southampton U23 v Newcastle U23 | W | 2-1 |
| England U23 Premier League Cup | 2019/02/08 19:00 | Newcastle U23 v Southampton U23 | L | 3-0 |
| England Premier League 2 | 2018/12/14 19:00 | Southampton U23 v Newcastle U23 | W | 2-1 |
| England U23 Premier League Cup | 2018/11/09 19:00 | Southampton U23 v Newcastle U23 | D | 1-1 |
| England Premier League 2 | 2018/09/14 18:00 | Newcastle U23 v Southampton U23 | W | 0-1 |
| England Premier League 2 | 2018/02/19 19:00 | Newcastle U23 v Southampton U23 | W | 1-5 |
| England Premier League 2 | 2017/10/16 18:00 | Southampton U23 v Newcastle U23 | W | 6-2 |
| England U23 Premier League Cup | 2017/02/28 14:04 | Newcastle U23 v Southampton U23 | L | 2-0 |
Home History
| England U23 Premier League Cup | 2021/09/02 18:00 | Arsenal U23 v Southampton U23 | D | 1-1 |
| England Premier League 2 | 2021/08/29 11:00 | Middlesbrough U23 v Southampton U23 | L | 2-1 |
| England Premier League 2 | 2021/08/23 18:00 | Nottm Forest U23 v Southampton U23 | D | 0-0 |
| England Premier League 2 | 2021/08/15 13:00 | Southampton U23 v Norwich U23 | L | 0-3 |
| England Premier League 2 | 2021/05/07 18:00 | Everton U23 v Southampton U23 | L | 4-0 |
| England Premier League 2 | 2021/05/02 13:00 | Southampton U23 v Everton U23 | L | 0-5 |
| England Premier League 2 | 2021/04/19 18:00 | Leicester U23 v Southampton U23 | L | 7-1 |
| England Premier League 2 | 2021/04/12 18:00 | Chelsea U23 v Southampton U23 | L | 3-1 |
Away History
| England U23 Premier League Cup | 2021/09/06 17:00 | Watford U23 v Newcastle U23 | L | 2-0 |
| England Premier League 2 | 2021/08/27 18:00 | Newcastle U23 v Burnley U23 | W | 2-0 |
| England Premier League 2 | 2021/08/23 18:00 | Birmingham U23 v Newcastle U23 | W | 0-4 |
| England Premier League 2 | 2021/08/16 18:00 | Newcastle U23 v Reading U23 | D | 1-1 |
| Club Friendly List | 2021/07/18 13:00 | Harrogate Town v Newcastle U23 | L | 2-1 |
| England Premier League 2 | 2021/05/07 18:00 | Newcastle U23 v Aston Villa U23 | L | 1-2 |
| England Premier League 2 | 2021/05/02 13:00 | Aston Villa U23 v Newcastle U23 | D | 1-1 |
| England Premier League 2 | 2021/04/26 12:00 | Newcastle U23 v Crystal Palace U23 | W | 2-0 |