[51] Auburn 17-21 South Carolina [78] 2021-09-02 20:00
Stadium: Williams-Brice Stadium Round: 1
Home Manager: Shane Beamer Away Manager: Bryan Harsin
Head to Head
| NCAAF | 2020/10/17 16:00 | Auburn v South Carolina | L | 22-30 |
| NCAAF | 2014/10/25 23:30 | Auburn v South Carolina | W | 42-35 |
| NCAAF | 2011/10/01 12:00 | South Carolina v Auburn | W | 13-16 |
| NCAAF | 2010/12/04 12:00 | Auburn v South Carolina | W | 56-17 |
| NCAAF | 2010/09/25 12:00 | Auburn v South Carolina | W | 35-27 |
| NCAAF | 2006/09/28 12:00 | South Carolina v Auburn | W | 17-24 |
| NCAAF | 2005/10/01 12:00 | Auburn v South Carolina | W | 48-7 |
Home History
| NCAAF | 2021/01/01 18:00 | Auburn v Northwestern | L | 19-35 |
| NCAAF | 2020/12/13 00:30 | Auburn v Mississippi State | W | 24-10 |
| NCAAF | 2020/12/05 17:00 | Texas A&M v Auburn | L | 31-20 |
| NCAAF | 2020/11/28 20:30 | Auburn v Alabama | L | 13-42 |
| NCAAF | 2020/11/22 00:00 | Tennessee v Auburn | W | 17-30 |
| NCAAF | 2020/10/31 19:30 | LSU v Auburn | W | 11-48 |
| NCAAF | 2020/10/24 16:00 | Auburn v Mississippi | W | 35-28 |
| NCAAF | 2020/10/17 16:00 | Auburn v South Carolina | L | 22-30 |
Away History
| NCAAF | 2020/12/06 00:30 | South Carolina v Kentucky | L | 18-41 |
| NCAAF | 2020/11/29 00:30 | Georgia v South Carolina | L | 45-16 |
| NCAAF | 2020/11/22 00:30 | Missouri v South Carolina | L | 17-10 |
| NCAAF | 2020/11/15 00:30 | South Carolina v Mississippi | L | 42-59 |
| NCAAF | 2020/11/08 00:00 | Texas A&M v South Carolina | L | 48-3 |
| NCAAF | 2020/10/24 23:00 | South Carolina v LSU | L | 24-52 |
| NCAAF | 2020/10/17 16:00 | Auburn v South Carolina | W | 22-30 |
| NCAAF | 2020/10/10 16:00 | South Carolina v Vanderbilt | W | 41-7 |