[113] Club Africain 34-26 Eastern Michigan [49] 2021-09-20 05:00
Stadium: Rynearson Stadium Round: 1
Home Manager: Tim Albin Away Manager: Chris Creighton
Head to Head
| NCAAF | 2017/09/23 18:00 | Ohio v Eastern Michigan | W | 27-20 |
| NCAAF | 2016/10/15 18:00 | Eastern Michigan v Ohio | L | 27-20 |
| NCAAF | 2010/10/02 12:00 | Eastern Michigan v Ohio | W | 17-30 |
| NCAAF | 2007/10/13 12:00 | Ohio v Eastern Michigan | W | 48-42 |
| NCAAF | 2006/11/04 12:00 | Eastern Michigan v Ohio | W | 10-16 |
| NCAAF | 2002/10/12 12:00 | Ohio v Eastern Michigan | W | 55-27 |
Home History
| NCAAF | 2021/09/17 00:00 | Ohio v Lafayette | L | 14-49 |
| NCAAF | 2021/09/11 18:00 | Duquesne v Ohio | L | 28-26 |
| NCAAF | 2021/09/04 23:00 | Syracuse v Ohio | L | 29-9 |
| NCAAF | 2020/11/28 17:00 | Bowling Green v Ohio | W | 10-52 |
| NCAAF | 2020/11/11 00:00 | Akron v Ohio | W | 10-24 |
| NCAAF | 2020/11/05 00:00 | Ohio v Central Michigan | L | 27-30 |
| NCAAF | 2020/01/03 20:30 | Ohio v Nevada | W | 30-21 |
| NCAAF | 2019/11/26 23:00 | Ohio v Akron | W | 52-3 |
Away History
| NCAAF | 2021/09/18 19:30 | Eastern Michigan v Massachusetts | W | 42-28 |
| NCAAF | 2021/09/11 23:00 | Eastern Michigan v Wisconsin | L | 7-34 |
| NCAAF | 2021/09/03 23:00 | St.Francis (PA) v Eastern Michigan | W | 15-35 |
| NCAAF | 2020/12/12 17:00 | Northern Illinois v Eastern Michigan | W | 33-41 |
| NCAAF | 2020/12/05 19:00 | Eastern Michigan v Western Michigan | W | 53-42 |
| NCAAF | 2020/11/27 21:00 | Central Michigan v Eastern Michigan | L | 31-23 |
| NCAAF | 2020/11/19 00:00 | Toledo v Eastern Michigan | L | 45-28 |
| NCAAF | 2020/11/12 00:00 | Eastern Michigan v Ball State | L | 31-38 |