East Tennessee State 56-35 Western Carolina 2021-09-23 13:00
Stadium: Bob Waters Field at E.J. Whitmire Stadium Round: 1
Head to Head
| NCAAF | 2021/03/27 17:00 | Western Carolina v East Tennessee State | W | 17-24 |
| NCAAF | 2019/11/09 20:30 | East Tennessee State v Western Carolina | L | 20-23 |
| NCAAF | 2018/10/27 19:30 | East Tennessee State v Western Carolina | W | 45-43 |
| NCAAF | 2017/10/14 19:30 | Western Carolina v East Tennessee State | L | 49-10 |
Home History
| NCAAF | 2021/09/18 23:30 | Delaware State v East Tennessee State | W | 6-38 |
| NCAAF | 2021/09/11 23:30 | East Tennessee State v Virginia Wise Highland Cavaliers | W | 45-14 |
| NCAAF | 2021/09/05 00:00 | East Tennessee State v Vanderbilt | W | 23-3 |
| NCAAF | 2021/04/10 22:00 | East Tennessee State v Mercer | L | 13-21 |
| NCAAF | 2021/04/03 17:30 | East Tennessee State v VMI | W | 24-20 |
| NCAAF | 2021/03/27 17:00 | Western Carolina v East Tennessee State | W | 17-24 |
| NCAAF | 2021/03/20 17:00 | East Tennessee State v The Citadel | W | 28-21 |
| NCAAF | 2021/03/13 18:00 | Furman v East Tennessee State | L | 17-13 |
Away History
| NCAAF | 2021/09/18 18:30 | Samford v Western Carolina | L | 42-37 |
| NCAAF | 2021/09/11 23:00 | Western Carolina v Oklahoma | L | 0-76 |
| NCAAF | 2021/09/04 22:00 | Eastern Kentucky v Western Carolina | L | 31-28 |
| NCAAF | 2021/03/27 17:00 | Western Carolina v East Tennessee State | L | 17-24 |
| NCAAF | 2021/03/20 20:00 | Mercer v Western Carolina | L | 45-28 |
| NCAAF | 2021/03/13 18:00 | The Citadel v Western Carolina | W | 14-21 |
| NCAAF | 2021/03/06 18:00 | VMI v Western Carolina | L | 30-7 |
| NCAAF | 2021/02/27 18:00 | Western Carolina v Samford | L | 27-55 |