Stadium: Callaway Stadium Round: 1
| NCAAF | 2019/11/16 18:00 | Lagrange Panthers v Huntingdon Hawks | L | 21-45 |
| NCAAF | 2018/11/10 19:00 | Huntingdon Hawks v Lagrange Panthers | L | 42-14 |
| NCAAF | 2021/10/30 17:00 | Lagrange Panthers v Greensboro | W | 29-14 |
| NCAAF | 2021/10/23 18:00 | Maryville Scots v Lagrange Panthers | L | 52-16 |
| NCAAF | 2021/10/16 20:00 | Lagrange Panthers v Brevard Tornados | L | 10-20 |
| NCAAF | 2021/10/09 17:00 | Methodist Monarchs v Lagrange Panthers | L | 34-17 |
| NCAAF | 2021/09/25 17:00 | Lagrange Panthers v Nc Wesleyan Battling Bishops | L | 21-26 |
| NCAAF | 2021/09/18 17:00 | Southern Virginia Knights v Lagrange Panthers | W | 34-38 |
| NCAAF | 2021/09/11 18:00 | Lagrange Panthers v Berry Vikings | L | 21-34 |
| NCAAF | 2021/09/04 23:00 | Birmingham Southern Panthers v Lagrange Panthers | L | 42-17 |
| NCAAF | 2021/10/30 18:00 | Huntingdon Hawks v Nc Wesleyan Battling Bishops | W | 30-7 |
| NCAAF | 2021/10/23 16:00 | Greensboro v Huntingdon Hawks | W | 3-42 |
| NCAAF | 2021/10/16 18:00 | Huntingdon Hawks v Averett Cougars | W | 30-25 |
| NCAAF | 2021/10/09 17:00 | Southern Virginia Knights v Huntingdon Hawks | W | 20-48 |
| NCAAF | 2021/10/02 18:00 | Huntingdon Hawks v Methodist Monarchs | W | 48-21 |
| NCAAF | 2021/09/25 17:00 | Brevard Tornados v Huntingdon Hawks | W | 14-21 |
| NCAAF | 2021/09/11 23:00 | Huntingdon Hawks v Birmingham Southern Panthers | L | 9-48 |
| NCAAF | 2021/09/04 17:00 | Huntingdon Hawks v Wisconsin Oshkosh | L | 24-28 |