[14] Preston 4-1 Middlesbrough [7] 2022-01-17 21:30
Stadium: Deepdale Round: 46
Referee: Tim Robinson Home Manager: Ryan Lowe Away Manager: Chris Wilder
Head to Head
| England Championship | 2021/11/23 19:45 | Middlesbrough v Preston | W | 1-2 |
| England Championship | 2021/03/16 19:00 | Middlesbrough v Preston | L | 2-0 |
| England Championship | 2020/12/09 19:00 | Preston v Middlesbrough | W | 3-0 |
| England Championship | 2020/01/01 15:00 | Preston v Middlesbrough | L | 0-2 |
| England Championship | 2019/10/01 18:45 | Middlesbrough v Preston | D | 1-1 |
| England Championship | 2019/03/13 19:45 | Middlesbrough v Preston | W | 1-2 |
| England Championship | 2018/11/27 19:45 | Preston v Middlesbrough | D | 1-1 |
| England EFL Cup | 2018/09/25 18:45 | Preston v Middlesbrough | L | 5-6 |
Home History
| England Championship | 2022/01/15 15:00 | Preston v Birmingham | D | 1-1 |
| England FA Cup | 2022/01/09 14:00 | Cardiff v Preston | D | 1-1 |
| England Championship | 2022/01/03 15:00 | Stoke v Preston | W | 1-2 |
| England Championship | 2021/12/11 15:00 | Preston v Barnsley | W | 2-1 |
| England Championship | 2021/12/04 15:00 | Blackburn v Preston | L | 1-0 |
| England Championship | 2021/11/27 12:30 | Preston v Fulham | D | 1-1 |
| England Championship | 2021/11/23 19:45 | Middlesbrough v Preston | W | 1-2 |
| England Championship | 2021/11/20 15:00 | Preston v Cardiff | L | 1-2 |
Away History
| England Championship | 2022/01/15 15:00 | Middlesbrough v Reading | W | 2-1 |
| England FA Cup | 2022/01/08 12:15 | Mansfield v Middlesbrough | W | 2-3 |
| England Championship | 2021/12/29 19:45 | Blackpool v Middlesbrough | W | 1-2 |
| England Championship | 2021/12/26 15:00 | Middlesbrough v Nottm Forest | W | 2-0 |
| England Championship | 2021/12/18 12:30 | Middlesbrough v Bournemouth | W | 1-0 |
| England Championship | 2021/12/11 15:00 | Stoke v Middlesbrough | D | 0-0 |
| England Championship | 2021/12/04 15:00 | Middlesbrough v Swansea | W | 1-0 |
| England Championship | 2021/11/27 15:00 | Huddersfield v Middlesbrough | W | 1-2 |