Stadium: Joseph J. Gentile Center
Home Manager: Cindy Stein Away Manager: Kate Achter
| WNCAAB | 2021/01/31 21:00 | Southern Illinois Women v Loyola Chicago Women | L | 46-55 |
| WNCAAB | 2021/01/30 19:00 | Loyola Chicago Women v Southern Illinois Women | L | 53-46 |
| WNCAAB | 2020/03/06 00:00 | Southern Illinois Women v Loyola Chicago Women | W | 58-41 |
| WNCAAB | 2020/01/05 19:00 | Loyola Chicago Women v Southern Illinois Women | L | 51-49 |
| WNCAAB | 2019/02/23 01:00 | Loyola Chicago Women v Southern Illinois Women | W | 41-64 |
| WNCAAB | 2019/01/27 20:00 | Southern Illinois Women v Loyola Chicago Women | W | 74-63 |
| WNCAAB | 2018/02/18 19:00 | Loyola Chicago Women v Southern Illinois Women | L | 62-53 |
| WNCAAB | 2018/01/20 00:00 | Southern Illinois Women v Loyola Chicago Women | W | 62-46 |
| WNCAAB | 2021/03/12 17:00 | Southern Illinois Women v Missouri State Women | L | 59-70 |
| WNCAAB | 2021/03/11 22:30 | Indiana State Women v Southern Illinois Women | W | 89-90 |
| WNCAAB | 2021/03/06 22:00 | Southern Illinois Women v Northern Iowa Women | L | 41-64 |
| WNCAAB | 2021/03/05 22:00 | Southern Illinois Women v Northern Iowa Women | L | 56-67 |
| WNCAAB | 2021/02/28 22:00 | Valparaiso Women v Southern Illinois Women | L | 70-63 |
| WNCAAB | 2021/02/27 22:00 | Valparaiso Women v Southern Illinois Women | L | 75-64 |
| WNCAAB | 2021/02/25 00:00 | Missouri State Women v Southern Illinois Women | L | 67-55 |
| WNCAAB | 2021/02/20 21:00 | Indiana State Women v Southern Illinois Women | W | 52-76 |
| WNCAAB | 2021/03/21 16:00 | Abilene Christian Women v Loyola Chicago Women | W | 55-74 |
| WNCAAB | 2021/03/20 16:00 | Manhattan Women v Loyola Chicago Women | L | 56-51 |
| WNCAAB | 2021/03/19 18:30 | Loyola Chicago Women v Stetson Women | L | 45-49 |
| WNCAAB | 2021/03/14 00:00 | Loyola Chicago Women v Bradley Women | L | 56-70 |
| WNCAAB | 2021/03/13 02:00 | Loyola Chicago Women v Illinois State Women | W | 61-60 |
| WNCAAB | 2021/03/06 21:00 | Illinois State Women v Loyola Chicago Women | L | 60-45 |
| WNCAAB | 2021/03/05 21:00 | Illinois State Women v Loyola Chicago Women | L | 64-61 |
| WNCAAB | 2021/02/28 23:00 | Loyola Chicago Women v Missouri State Women | L | 45-59 |