Stadium: William H. Detrick Gymnasium
Home Manager: Brett Nelson Away Manager: Patrick Sellers
| NCAAB | 2021/02/25 00:00 | Holy Cross v Boston U | W | 86-75 |
| NCAAB | 2021/02/21 20:00 | Army v Holy Cross | W | 51-67 |
| NCAAB | 2021/02/20 20:00 | Holy Cross v Army | L | 65-69 |
| NCAAB | 2021/02/17 22:00 | Boston U v Holy Cross | L | 78-69 |
| NCAAB | 2021/02/14 22:00 | Holy Cross v Boston U | L | 68-86 |
| NCAAB | 2021/02/13 19:00 | Boston U v Holy Cross | W | 65-82 |
| NCAAB | 2021/01/31 22:00 | Colgate v Holy Cross | L | 78-60 |
| NCAAB | 2021/01/30 19:00 | Colgate v Holy Cross | L | 74-63 |
| NCAAB | 2021/02/26 21:00 | Wagner v Central Connecticut | W | 77-83 |
| NCAAB | 2021/02/26 00:00 | Wagner v Central Connecticut | L | 83-63 |
| NCAAB | 2021/02/21 21:00 | Central Connecticut v LIU Brooklyn | L | 79-81 |
| NCAAB | 2021/02/21 00:00 | Central Connecticut v LIU Brooklyn | L | 74-87 |
| NCAAB | 2021/02/17 22:00 | Sacred Heart v Central Connecticut | L | 82-70 |
| NCAAB | 2021/02/13 00:00 | Merrimack v Central Connecticut | L | 72-52 |
| NCAAB | 2021/02/12 00:00 | Merrimack v Central Connecticut | L | 62-46 |
| NCAAB | 2021/01/31 21:00 | Central Connecticut v St Francis PA | W | 85-77 |