Stadium: Hard Rock Hotel Riviera Maya
Home Manager: Dan Muller Away Manager: Travis Ford
| NCAAB | 2021/03/05 02:08 | Illinois St v Northern Iowa | L | 60-65 |
| NCAAB | 2021/02/27 23:00 | Northern Iowa v Illinois St | L | 94-87 |
| NCAAB | 2021/02/27 02:00 | Northern Iowa v Illinois St | L | 70-56 |
| NCAAB | 2021/02/19 00:00 | Illinois St v Bradley | W | 88-71 |
| NCAAB | 2021/02/14 21:00 | Illinois St v Southern Illinois | L | 49-59 |
| NCAAB | 2021/02/13 21:00 | Illinois St v Southern Illinois | W | 80-55 |
| NCAAB | 2021/02/07 20:00 | Missouri State v Illinois St | L | 72-62 |
| NCAAB | 2021/02/06 20:00 | Missouri State v Illinois St | L | 74-67 |
| NIT | 2021/03/20 21:00 | Mississippi State v St Louis | L | 74-68 |
| NCAAB | 2021/03/06 23:00 | St Louis v St. Bonaventure | L | 53-71 |
| NCAAB | 2021/03/05 18:00 | Massachusetts v St Louis | W | 72-86 |
| NCAAB | 2021/03/01 23:00 | Massachusetts v St Louis | W | 57-78 |
| NCAAB | 2021/02/27 00:00 | Richmond v St Louis | W | 67-72 |
| NCAAB | 2021/02/23 23:00 | St Louis v VA Commonwealth | L | 65-67 |
| NCAAB | 2021/02/20 00:00 | St Louis v Dayton | L | 53-76 |
| NCAAB | 2021/02/17 02:00 | La Salle v St Louis | W | 57-78 |