[4] Cruz Azul 1-2 South Korea [18] 2022-01-28 15:00
Stadium: Estadio Azteca Round: 7
Referee: Cesar Ramos Palazuelos Home Manager: Juan Reynoso Away Manager: Pedro Caixinha
Head to Head
| Mexico Liga MX | 2021/08/01 23:00 | Santos Laguna v Cruz Azul | D | 1-1 |
| Mexico Liga MX | 2021/05/31 01:15 | Cruz Azul v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2021/05/28 02:00 | Santos Laguna v Cruz Azul | W | 0-1 |
| Mexico Liga MX | 2021/01/11 01:06 | Santos Laguna v Cruz Azul | L | 1-0 |
| Mexico Liga MX | 2020/07/26 02:00 | Cruz Azul v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2020/01/25 23:00 | Cruz Azul v Santos Laguna | W | 3-0 |
| Mexico Liga MX | 2019/11/11 00:45 | Santos Laguna v Cruz Azul | L | 3-1 |
| Mexico Liga MX | 2019/02/16 23:00 | Cruz Azul v Santos Laguna | L | 1-2 |
Home History
| Mexico Liga MX | 2022/01/23 03:06 | Monterrey v Cruz Azul | D | 2-2 |
| Mexico Liga MX | 2022/01/16 03:00 | Cruz Azul v Juarez FC | W | 1-0 |
| Mexico Liga MX | 2022/01/09 03:00 | Cruz Azul v Tijuana | W | 2-0 |
| World Club Friendlies | 2021/12/21 02:00 | Venados FC v Cruz Azul | W | 1-2 |
| Mexico Liga MX | 2021/11/22 01:15 | Cruz Azul v Monterrey | L | 1-4 |
| Mexico Liga MX | 2021/11/07 23:00 | Unam Pumas v Cruz Azul | L | 4-3 |
| Mexico Liga MX | 2021/11/04 03:00 | Cruz Azul v Leon | L | 0-1 |
| Mexico Liga MX | 2021/10/31 23:05 | Cruz Azul v Club America | W | 2-1 |
Away History
| Mexico Liga MX | 2022/01/24 01:00 | Santos Laguna v Necaxa | L | 1-4 |
| Mexico Liga MX | 2022/01/16 18:00 | Toluca v Santos Laguna | L | 3-1 |
| Mexico Liga MX | 2022/01/13 02:06 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2021/11/29 00:00 | Tigres UANL v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2021/11/26 03:05 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexico Liga MX | 2021/11/21 01:00 | Santos Laguna v Atletico San Luis | W | 2-0 |
| Mexico Liga MX | 2021/11/08 01:06 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2021/11/05 01:00 | Unam Pumas v Santos Laguna | W | 0-3 |