[5] Nacional Asuncion 3-1 Guairena FC [7] 2022-01-06 18:00
Stadium: Estadio Arsenio Erico Round: 11
Referee: Jose Mendez Home Manager: Carlos Bonet Caceres Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2021/11/08 23:30 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2021/08/20 23:30 | Nacional Asuncion v Guairena FC | L | 0-2 |
| Paraguay Division Profesional | 2021/04/30 22:00 | Nacional Asuncion v Guairena FC | L | 1-3 |
| Paraguay Division Profesional | 2021/03/01 21:30 | Guairena FC v Nacional Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/11/22 21:30 | Nacional Asuncion v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2020/08/07 20:00 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2020/01/18 21:00 | Nacional Asuncion v Guairena FC | W | 3-0 |
Home History
| Paraguay Division Profesional | 2021/12/05 22:30 | Nacional Asuncion v Olimpia Asuncion | L | 1-3 |
| Paraguay Division Profesional | 2021/11/26 22:30 | Sol de America v Nacional Asuncion | L | 3-0 |
| Paraguay Division Profesional | 2021/11/21 23:15 | Nacional Asuncion v Cerro Porteno | L | 1-5 |
| Paraguay Division Profesional | 2021/11/08 23:30 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2021/10/29 22:30 | Nacional Asuncion v River Plate Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/10/24 23:15 | Libertad Asuncion v Nacional Asuncion | W | 1-2 |
| Paraguay Division Profesional | 2021/10/16 22:30 | Nacional Asuncion v Sportivo Luqueno | D | 0-0 |
| Paraguay Division Profesional | 2021/10/03 21:00 | Guarani Asuncion v Nacional Asuncion | D | 1-1 |
Away History
| Paraguay Division Profesional | 2021/12/04 21:15 | Sportivo Luqueno v Guairena FC | W | 0-1 |
| Paraguay Division Profesional | 2021/11/28 22:00 | Guairena FC v Guarani Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/11/19 22:00 | 12 de Octubre v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2021/11/08 23:30 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Cup | 2021/11/04 20:45 | Olimpia Asuncion v Guairena FC | L | 2-0 |
| Paraguay Division Profesional | 2021/10/31 23:15 | Sol de America v Guairena FC | L | 3-0 |
| Paraguay Division Profesional | 2021/10/25 21:30 | Guairena FC v Cerro Porteno | L | 0-2 |
| Paraguay Cup | 2021/10/20 23:00 | Sportivo Ameliano v Guairena FC | W | 4-5 |