[3] Sam Houston St 3-1 Cheltenham [14] 2022-01-17 19:45
Stadium: Stadium MK Round: 25
Home Manager: Liam Manning Away Manager: Michael James Duff
Head to Head
| England League 1 | 2021/09/04 14:00 | Cheltenham v Milton Keynes Dons | D | 1-1 |
| England League 2 | 2018/12/26 15:00 | Cheltenham v Milton Keynes Dons | L | 3-1 |
| England League 2 | 2018/10/06 14:00 | Milton Keynes Dons v Cheltenham | W | 3-0 |
Home History
| England League 1 | 2022/01/15 15:00 | Portsmouth v Milton Keynes Dons | W | 1-2 |
| England League 1 | 2022/01/11 19:45 | Milton Keynes Dons v AFC Wimbledon | W | 1-0 |
| England League 1 | 2022/01/08 15:00 | Accrington Stanley v Milton Keynes Dons | D | 1-1 |
| England EFL Trophy | 2022/01/04 19:00 | Charlton v Milton Keynes Dons | L | 1-0 |
| England League 1 | 2022/01/01 15:00 | Milton Keynes Dons v Gillingham | D | 0-0 |
| England League 1 | 2021/12/26 15:00 | Lincoln City v Milton Keynes Dons | W | 2-3 |
| England League 1 | 2021/12/11 15:00 | Milton Keynes Dons v Oxford Utd | L | 1-2 |
| England League 1 | 2021/12/08 19:45 | Milton Keynes Dons v Plymouth | D | 1-1 |
Away History
| England League 1 | 2022/01/15 15:00 | Cheltenham v Charlton | D | 1-1 |
| England League 1 | 2022/01/08 15:00 | Cheltenham v Burton Albion | D | 1-1 |
| England League 1 | 2022/01/01 15:00 | Oxford Utd v Cheltenham | D | 1-1 |
| England League 1 | 2021/12/26 15:00 | Cheltenham v Plymouth | L | 0-2 |
| England League 1 | 2021/12/18 15:00 | Shrewsbury v Cheltenham | L | 3-1 |
| England League 1 | 2021/12/11 15:00 | Cheltenham v Lincoln City | D | 2-2 |
| England League 1 | 2021/12/07 19:45 | Cheltenham v Cambridge Utd | L | 0-5 |
| England FA Cup | 2021/12/04 15:00 | AFC Wimbledon v Cheltenham | L | 4-3 |