Head to Head
| MLB Exhibition | 2022/04/04 20:05 | CHI White Sox v CHI Cubs | L | 9-15 |
| MLB Spring Training | 2022/03/17 20:05 | CHI Cubs v CHI White Sox | W | 3-4 |
| MLB | 2021/08/29 18:10 | CHI Cubs v CHI White Sox | W | 1-13 |
| MLB | 2021/08/28 23:10 | CHI Cubs v CHI White Sox | L | 7-0 |
| MLB | 2021/08/28 00:10 | CHI Cubs v CHI White Sox | W | 13-17 |
| MLB | 2021/08/08 23:09 | CHI White Sox v CHI Cubs | W | 9-3 |
| MLB | 2021/08/07 18:20 | CHI White Sox v CHI Cubs | W | 4-0 |
| MLB | 2021/08/06 18:20 | CHI White Sox v CHI Cubs | W | 8-6 |
Home History
| MLB | 2022/04/27 18:10 | KC Royals v CHI White Sox | W | 3-7 |
| MLB | 2022/04/26 23:10 | KC Royals v CHI White Sox | L | 6-0 |
| MLB | 2022/04/24 18:10 | CHI White Sox v MIN Twins | L | 4-6 |
| MLB | 2022/04/23 20:05 | CHI White Sox v MIN Twins | L | 2-9 |
| MLB | 2022/04/23 00:10 | CHI White Sox v MIN Twins | L | 1-2 |
| MLB | 2022/04/21 17:10 | CHI White Sox v CLE Guardians | L | 3-6 |
| MLB | 2022/04/20 21:40 | CHI White Sox v CLE Guardians | L | 1-2 |
| MLB | 2022/04/20 18:10 | CHI White Sox v CLE Guardians | L | 1-11 |
Away History
| MLB | 2022/04/27 23:20 | CHI Cubs v ATL Braves | W | 6-3 |
| MLB | 2022/04/26 23:20 | CHI Cubs v ATL Braves | L | 1-3 |
| MLB | 2022/04/24 18:20 | PIT Pirates v CHI Cubs | L | 4-3 |
| MLB | 2022/04/23 18:20 | PIT Pirates v CHI Cubs | W | 0-21 |
| MLB | 2022/04/23 00:05 | PIT Pirates v CHI Cubs | L | 4-2 |
| MLB | 2022/04/21 23:40 | PIT Pirates v CHI Cubs | L | 4-3 |
| MLB | 2022/04/20 22:30 | TB Rays v CHI Cubs | L | 8-2 |
| MLB | 2022/04/19 23:40 | TB Rays v CHI Cubs | L | 6-5 |