[3] Fresno State 17-45 USC [1] 2022-04-23 14:30
Stadium: Los Angeles Memorial Coliseum Round: 1
Home Manager: Jeff Tedford Away Manager: Lincoln Riley
Head to Head
| NCAAF | 2019/09/01 02:30 | Fresno State v USC | L | 23-31 |
| NCAAF | 2014/08/30 23:30 | USC v Fresno State | L | 52-13 |
| NCAAF | 2005/11/19 12:00 | USC v Fresno State | L | 50-42 |
Home History
| NCAAF Bowl Games | 2021/12/18 19:15 | UTEP v Fresno State | W | 24-31 |
| NCAAF | 2021/11/25 20:30 | Fresno State v San Jose State | W | 40-9 |
| NCAAF | 2021/11/14 00:00 | New Mexico v Fresno State | W | 7-34 |
| NCAAF | 2021/11/06 23:00 | Boise State v Fresno State | L | 40-14 |
| NCAAF | 2021/10/31 02:30 | Fresno State v San Diego State | W | 30-20 |
| NCAAF | 2021/10/23 23:00 | Nevada v Fresno State | W | 32-34 |
| NCAAF | 2021/10/16 19:30 | Fresno State v Wyoming | W | 17-0 |
| NCAAF | 2021/10/03 03:00 | Fresno State v Hawaii | L | 24-27 |
Away History
| NCAAF | 2021/12/05 04:00 | USC v California | L | 14-24 |
| NCAAF | 2021/11/28 03:30 | BYU v USC | L | 35-31 |
| NCAAF | 2021/11/20 21:00 | UCLA v USC | L | 62-33 |
| NCAAF | 2021/11/07 02:30 | USC v Arizona State | L | 16-31 |
| NCAAF | 2021/10/30 23:00 | Arizona v USC | W | 34-41 |
| NCAAF | 2021/10/23 23:30 | USC v Notre Dame | L | 16-31 |
| NCAAF | 2021/10/10 00:00 | Utah v USC | L | 42-26 |
| NCAAF | 2021/10/02 18:00 | USC v Colorado | W | 37-14 |