[20] Southampton 2-2 Leeds [7] 2022-04-12 06:00
Stadium: St. Mary's Stadium Round: 2
Referee: Tony Harrington Home Manager: Ralph Hasenhuttl Away Manager: Jesse Marsch
Head to Head
| England Premier League | 2022/04/02 14:00 | Leeds v Southampton | D | 1-1 |
| England Premier League | 2021/10/16 14:00 | Southampton v Leeds | W | 1-0 |
| England Premier League | 2021/05/18 17:00 | Southampton v Leeds | L | 0-2 |
| England Premier League | 2021/02/23 18:00 | Leeds v Southampton | L | 3-0 |
Home History
| England Premier League | 2022/04/09 14:00 | Southampton v Chelsea | L | 0-6 |
| England Premier League | 2022/04/02 14:00 | Leeds v Southampton | D | 1-1 |
| England FA Cup | 2022/03/20 15:00 | Southampton v Man City | L | 1-4 |
| England Premier League | 2022/03/13 14:00 | Southampton v Watford | L | 1-2 |
| England Premier League | 2022/03/10 19:30 | Southampton v Newcastle | L | 1-2 |
| England Premier League | 2022/03/05 15:00 | Aston Villa v Southampton | L | 4-0 |
| England FA Cup | 2022/03/02 19:30 | Southampton v West Ham | W | 3-1 |
| England Premier League | 2022/02/25 20:00 | Southampton v Norwich | W | 2-0 |
Away History
| England Premier League | 2022/04/09 14:00 | Watford v Leeds | W | 0-3 |
| England Premier League | 2022/04/02 14:00 | Leeds v Southampton | D | 1-1 |
| England Premier League | 2022/03/18 20:00 | Wolverhampton v Leeds | W | 2-3 |
| England Premier League | 2022/03/13 14:00 | Leeds v Norwich | W | 2-1 |
| England Premier League | 2022/03/10 19:45 | Leeds v Aston Villa | L | 0-3 |
| England Premier League | 2022/03/05 12:30 | Leicester v Leeds | L | 1-0 |
| England Premier League | 2022/02/26 12:30 | Leeds v Tottenham | L | 0-4 |
| England Premier League | 2022/02/23 19:45 | Liverpool v Leeds | L | 6-0 |