Home History
| England EFL Trophy | 2022/08/30 18:00 | Doncaster v Newcastle U21 | D | 0-0 |
| England Premier League 2 | 2022/08/26 18:00 | Newcastle U21 v Derby U21 | W | 4-0 |
| England Premier League 2 | 2022/08/21 13:00 | Norwich U21 v Newcastle U21 | L | 4-2 |
| England Premier League 2 | 2022/08/15 18:00 | Newcastle U21 v Stoke U21 | L | 0-1 |
| England Premier League 2 | 2022/08/08 16:00 | West Brom U21 v Newcastle U21 | L | 2-1 |
| England EFL Trophy | 2021/11/09 19:45 | Mansfield v Newcastle U21 | L | 6-3 |
| England EFL Trophy | 2021/10/05 18:45 | Harrogate Town v Newcastle U21 | L | 2-0 |
| England EFL Trophy | 2021/08/31 18:00 | Sheff Wed v Newcastle U21 | L | 3-0 |
Away History
| England EFL Trophy | 2022/08/30 18:00 | Forest Green v Southampton U21 | L | 3-1 |
| England Premier League 2 | 2022/08/26 18:00 | Southampton U21 v Norwich U21 | D | 1-1 |
| England Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| England Premier League 2 | 2022/08/12 17:00 | Southampton U21 v West Brom U21 | W | 4-1 |
| England Premier League 2 | 2022/08/08 18:00 | Nottm Forest U21 v Southampton U21 | W | 1-3 |
| England EFL Trophy | 2021/11/09 19:00 | Crawley Town v Southampton U21 | W | 0-4 |
| England EFL Trophy | 2021/10/05 18:00 | Charlton v Southampton U21 | L | 4-1 |
| England EFL Trophy | 2021/09/14 18:00 | Leyton Orient v Southampton U21 | L | 1-0 |