Stadium: Edwin Fauver Stadium Round: 1
| NCAAF | 2021/10/02 16:00 | Rpi Engineers v Rochester Yellowjackets | L | 38-22 |
| NCAAF | 2019/10/05 16:05 | Rpi Engineers v Rochester Yellowjackets | L | 38-0 |
| NCAAF | 2018/10/27 16:00 | Rochester Yellowjackets v Rpi Engineers | L | 0-42 |
| NCAAF | 2021/11/13 17:00 | Rochester Yellowjackets v Hobart Statesmen | L | 0-31 |
| NCAAF | 2021/11/06 17:00 | Hartwick Hawks v Rochester Yellowjackets | W | 28-42 |
| NCAAF | 2021/10/30 17:00 | St Lawrence Saints v Rochester Yellowjackets | L | 34-10 |
| NCAAF | 2021/10/23 16:00 | Rochester Yellowjackets v Union Dutchmen | L | 9-35 |
| NCAAF | 2021/10/16 20:00 | Buffalo State Bengals v Rochester Yellowjackets | W | 7-14 |
| NCAAF | 2021/10/09 16:00 | Rochester Yellowjackets v Ithaca Bombers | L | 14-37 |
| NCAAF | 2021/10/02 16:00 | Rpi Engineers v Rochester Yellowjackets | L | 38-22 |
| NCAAF | 2021/09/18 16:00 | Brockport Golden Eagles v Rochester Yellowjackets | L | 16-7 |
| NCAAF | 2021/12/04 18:00 | North Central Illinois v Rpi Engineers | L | 55-6 |
| NCAAF | 2021/11/27 17:00 | Cortland Red Dragons v Rpi Engineers | W | 14-21 |
| NCAAF | 2021/11/20 17:00 | Endicott Gulls v Rpi Engineers | W | 14-20 |
| NCAAF | 2021/11/13 17:00 | Union Dutchmen v Rpi Engineers | W | 17-19 |
| NCAAF | 2021/11/13 16:00 | Union College Bulldogs v Rpi Engineers | W | 17-19 |
| NCAAF | 2021/11/06 17:00 | St Lawrence Saints v Rpi Engineers | W | 20-22 |
| NCAAF | 2021/10/30 16:00 | Rpi Engineers v Ithaca Bombers | W | 14-11 |
| NCAAF | 2021/10/16 17:00 | Hobart Statesmen v Rpi Engineers | L | 10-9 |