Stadium: Ralph Stocker Stadium Round: 1
| NCAAF | 2021/09/18 18:00 | N. Mexico H. Cowboys v Colorado Mesa University Mavericks | W | 37-56 |
| NCAAF | 2019/11/16 20:00 | Colorado Mesa University Mavericks v N. Mexico H. Cowboys | W | 51-13 |
| NCAAF | 2018/11/10 20:00 | N. Mexico H. Cowboys v Colorado Mesa University Mavericks | W | 24-52 |
| NCAAF | 2021/11/13 19:00 | South Dakota Mines Hardrockers v Colorado Mesa University Mavericks | W | 10-13 |
| NCAAF | 2021/11/06 19:00 | Colorado Mesa University Mavericks v Black Hills State | W | 52-9 |
| NCAAF | 2021/10/30 19:00 | Western State Colorado Mountaineers v Colorado Mesa University Mavericks | L | 23-9 |
| NCAAF | 2021/10/23 19:00 | Colorado Mesa University Mavericks v Colorado School of Mines | W | 26-21 |
| NCAAF | 2021/10/16 18:00 | Fort Lewis Skyhawks v Colorado Mesa University Mavericks | W | 3-55 |
| NCAAF | 2021/10/10 00:00 | Colorado Mesa University Mavericks v Adams State Grizzlies | W | 49-14 |
| NCAAF | 2021/10/02 20:00 | Colorado State Pueblo Thunderwolves v Colorado Mesa University Mavericks | L | 19-13 |
| NCAAF | 2021/09/25 19:00 | Colorado Mesa University Mavericks v Chadron State Eagles | W | 24-17 |
| NCAAF | 2021/11/20 19:00 | Western New Mexico Mustangs v N. Mexico H. Cowboys | W | 28-31 |
| NCAAF | 2021/11/06 18:00 | N. Mexico H. Cowboys v South Dakota Mines Hardrockers | L | 17-40 |
| NCAAF | 2021/10/30 19:00 | N. Mexico H. Cowboys v Adams State Grizzlies | W | 58-28 |
| NCAAF | 2021/10/23 19:00 | Black Hills State v N. Mexico H. Cowboys | W | 10-24 |
| NCAAF | 2021/10/16 19:00 | N. Mexico H. Cowboys v Colorado State Pueblo Thunderwolves | W | 28-21 |
| NCAAF | 2021/10/09 19:00 | Western State Colorado Mountaineers v N. Mexico H. Cowboys | L | 45-38 |
| NCAAF | 2021/10/02 18:00 | N. Mexico H. Cowboys v Chadron State Eagles | L | 16-46 |
| NCAAF | 2021/09/25 23:00 | Tarleton State v N. Mexico H. Cowboys | L | 40-21 |