Stadium: Mihalik-Thompson Stadium Round: 1
| NCAAF | 2021/10/23 16:00 | Mercyhurst v Slippery Rock | W | 17-20 |
| NCAAF | 2019/10/05 16:00 | Mercyhurst v Slippery Rock | W | 14-45 |
| NCAAF | 2018/09/29 22:00 | Slippery Rock v Mercyhurst | W | 41-21 |
| NCAAF | 2021/11/20 17:00 | Notre Dame Falcons v Slippery Rock | L | 33-25 |
| NCAAF | 2021/11/06 17:00 | Slippery Rock v California Vulcans | W | 38-26 |
| NCAAF | 2021/10/30 16:00 | Gannon University Golden Knights v Slippery Rock | W | 21-63 |
| NCAAF | 2021/10/23 16:00 | Mercyhurst v Slippery Rock | W | 17-20 |
| NCAAF | 2021/10/16 17:00 | Slippery Rock v Iup Crimson Hawks | L | 21-48 |
| NCAAF | 2021/10/09 18:00 | Edinboro v Slippery Rock | W | 13-49 |
| NCAAF | 2021/10/02 22:00 | Slippery Rock v Clarion Golden Eagles | W | 75-0 |
| NCAAF | 2021/09/25 22:00 | Seton Hill Griffins v Slippery Rock | W | 17-41 |
| NCAAF | 2021/11/13 18:00 | Shippensburg Raiders v Mercyhurst | L | 17-13 |
| NCAAF | 2021/11/06 16:00 | Mercyhurst v Gannon University Golden Knights | W | 24-13 |
| NCAAF | 2021/10/30 16:00 | Clarion Golden Eagles v Mercyhurst | W | 20-38 |
| NCAAF | 2021/10/23 16:00 | Mercyhurst v Slippery Rock | L | 17-20 |
| NCAAF | 2021/10/16 16:00 | Edinboro v Mercyhurst | W | 20-27 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | L | 17-19 |
| NCAAF | 2021/10/02 19:00 | California Vulcans v Mercyhurst | L | 37-0 |
| NCAAF | 2021/09/25 17:00 | Mercyhurst v Iup Crimson Hawks | L | 13-48 |