Stadium: Macalester Stadium Round: 1
| NCAAF | 2021/11/06 18:00 | St Scholastica Saints v Macalester Scots | W | 14-28 |
| NCAAF | 2021/10/31 00:00 | Macalester Scots v Hamline Pipers | W | 23-13 |
| NCAAF | 2021/10/23 18:00 | Bethel Royals v Macalester Scots | L | 63-10 |
| NCAAF | 2021/10/16 18:00 | Augsburg Auggies v Macalester Scots | L | 37-29 |
| NCAAF | 2021/10/09 18:00 | Macalester Scots v Concordia-Moorhead Cobbers | L | 27-34 |
| NCAAF | 2021/10/02 18:00 | Macalester Scots v Carleton Knights | L | 10-24 |
| NCAAF | 2021/09/25 18:00 | St Olaf Oles v Macalester Scots | L | 40-27 |
| NCAAF | 2021/09/11 23:00 | Trinity Tigers v Macalester Scots | L | 64-0 |
| NCAAF | 2021/11/06 18:00 | Gustavus Adolphus Gusties v St Olaf Oles | L | 29-14 |
| NCAAF | 2021/10/30 18:00 | St Olaf Oles v Bethel Royals | L | 14-35 |
| NCAAF | 2021/10/23 18:00 | St Olaf Oles v St Scholastica Saints | W | 41-14 |
| NCAAF | 2021/10/16 18:00 | St Johns Johnnies v St Olaf Oles | L | 56-0 |
| NCAAF | 2021/10/09 18:00 | St Olaf Oles v Carleton Knights | W | 23-14 |
| NCAAF | 2021/10/02 18:00 | Augsburg Auggies v St Olaf Oles | L | 56-28 |
| NCAAF | 2021/09/25 18:00 | St Olaf Oles v Macalester Scots | W | 40-27 |
| NCAAF | 2021/09/11 19:00 | Luther Norse v St Olaf Oles | W | 7-19 |