[5] Stefanos Tsitsipas 4-6,4-6 Holger N Rune [27] 2022-09-16 21:30
Stadium: Centre Court Round: 29 Ground: Hardcourt indoor
Head to Head
| French Open | 2022/05/30 12:00 | Holger Rune v Stefanos Tsitsipas | 7-5,3-6,6-3,6-4 |
Home History
| Davis Cup | 2022/09/16 10:00 | Mohamed Aziz Dougaz v Stefanos Tsitsipas | 6-7,2-6 |
| US Open | 2022/08/29 23:00 | Stefanos Tsitsipas v Daniel Elahi Galan | 0-6,1-6,6-3,5-7 |
| ATP Cincinnati | 2022/08/21 20:30 | Stefanos Tsitsipas v Borna Coric | 6-7,2-6 |
| ATP Cincinnati | 2022/08/20 23:55 | Daniil Medvedev v Stefanos Tsitsipas | 6-7,6-3,3-6 |
| ATP Cincinnati | 2022/08/19 19:00 | Stefanos Tsitsipas v John Isner | 7-6,5-7,6-3 |
| ATP Cincinnati | 2022/08/18 17:30 | Stefanos Tsitsipas v Diego Schwartzman | 6-3,6-3 |
| ATP Cincinnati | 2022/08/17 19:25 | Stefanos Tsitsipas v Filip Krajinovic | 6-3,6-4 |
| ATP Montreal | 2022/08/11 02:20 | Jack Draper v Stefanos Tsitsipas | 7-5,7-6 |
Away History
| US Open | 2022/09/03 15:00 | Cameron Norrie v Holger Rune | 7-5,6-4,6-1 |
| US Open | 2022/08/30 17:15 | Peter Gojowczyk v Holger Rune | 2-6,4-6,6-7 |
| ATP Cincinnati | 2022/08/15 18:00 | Holger Rune v Cameron Norrie | 6-7,6-4,4-6 |
| ATP Montreal | 2022/08/10 16:45 | Holger Rune v Pablo Carreno Busta | 0-6,3-6 |
| ATP Montreal | 2022/08/09 20:45 | Fabio Fognini v Holger Rune | 3-6,5-7 |
| ATP Washington | 2022/08/05 16:00 | Holger Rune v Jeffrey John Wolf | 5-7,6-4,3-6 |
| ATP Washington | 2022/08/03 16:00 | Holger Rune v Benoit Paire | 6-3,6-2 |
| ATP Umag | 2022/07/27 16:55 | Holger Rune v Bernabe Zapata Miralles | 6-3,3-6,2-6 |