Stadium: Minges Coliseum
Home Manager: Erik Martin Away Manager: Michael Schwartz
| NCAAB | 2021/11/10 00:00 | South Carolina State v East Carolina | L | 62-70 |
| NCAAB | 2015/12/23 00:00 | East Carolina v South Carolina State | L | 98-71 |
| NCAAB | 2022/03/10 23:00 | South Carolina State v Morgan State | L | 77-80 |
| NCAAB | 2022/03/04 00:30 | South Carolina State v North Carolina Central | L | 62-67 |
| NCAAB | 2022/03/01 00:30 | South Carolina State v Howard | L | 62-72 |
| NCAAB | 2022/02/26 23:00 | South Carolina State v Norfolk State | L | 59-63 |
| NCAAB | 2022/02/22 00:30 | Delaware State v South Carolina State | W | 74-79 |
| NCAAB | 2022/02/19 21:00 | Maryland Eastern-Shore v South Carolina State | W | 63-70 |
| NCAAB | 2022/02/15 00:30 | South Carolina State v Morgan State | L | 66-76 |
| NCAAB | 2022/02/12 21:00 | South Carolina State v Coppin State | W | 66-58 |
| NCAAB | 2022/03/10 18:00 | East Carolina v Cincinnati | L | 63-74 |
| NCAAB | 2022/03/05 20:00 | East Carolina v Wichita State | L | 62-70 |
| NCAAB | 2022/02/26 21:00 | Tulsa v East Carolina | W | 59-64 |
| NCAAB | 2022/02/24 00:00 | South Florida v East Carolina | W | 60-64 |
| NCAAB | 2022/02/20 19:00 | East Carolina v Central Florida | L | 66-69 |
| NCAAB | 2022/02/18 00:00 | East Carolina v South Florida | W | 65-57 |
| NCAAB | 2022/02/12 23:00 | SMU v East Carolina | L | 80-66 |
| NCAAB | 2022/02/09 01:00 | East Carolina v Tulsa | W | 73-71 |