Stadium: Lloyd Noble Center
Home Manager: Richie Riley Away Manager: Porter Moser
| NCAAB | 2022/03/29 00:00 | Coastal Carolina v South Alabama | L | 69-68 |
| NCAAB | 2022/03/22 00:00 | USC Upstate v South Alabama | W | 79-83 |
| NCAAB | 2022/03/17 00:00 | SE Louisiana v South Alabama | W | 68-70 |
| NCAAB | 2022/03/03 20:00 | Arkansas LR v South Alabama | L | 75-71 |
| NCAAB | 2022/02/26 20:00 | UT Arlington v South Alabama | W | 52-62 |
| NCAAB | 2022/02/24 01:00 | Texas State v South Alabama | L | 55-52 |
| NCAAB | 2022/02/19 21:30 | South Alabama v Appalachian State | L | 51-69 |
| NCAAB | 2022/02/18 00:00 | South Alabama v Coastal Carolina | W | 71-68 |
| NIT | 2022/03/21 00:00 | St. Bonaventure v Oklahoma | L | 70-68 |
| NIT | 2022/03/15 23:00 | Missouri State v Oklahoma | W | 72-89 |
| NCAAB | 2022/03/12 02:30 | Oklahoma v Texas Tech | L | 55-56 |
| NCAAB | 2022/03/11 00:00 | Oklahoma v Baylor Bears | W | 72-67 |
| NCAAB | 2022/03/05 21:00 | Oklahoma v Kansas State | W | 78-71 |
| NCAAB | 2022/03/02 00:00 | West Virginia v Oklahoma | W | 59-72 |
| NCAAB | 2022/02/26 18:00 | Oklahoma State v Oklahoma | W | 62-66 |
| NCAAB | 2022/02/23 01:00 | Oklahoma v Texas Tech | L | 42-66 |