Stadium: Horton Field House
Home Manager: Brian Barone Away Manager: Ryan Pedon
| NCAAB | 2011/11/17 12:00 | Illinois St v SIU Edwardsville | L | 68-38 |
| NCAAB | 2010/11/14 12:00 | Illinois St v SIU Edwardsville | L | 92-64 |
| NCAAB | 2009/11/15 12:00 | SIU Edwardsville v Illinois St | L | 60-82 |
| NCAAB | 2022/03/03 00:30 | SIU Edwardsville v Tennessee State | L | 62-77 |
| NCAAB | 2022/02/26 21:30 | Morehead State v SIU Edwardsville | W | 70-77 |
| NCAAB | 2022/02/25 01:30 | Austin Peay v SIU Edwardsville | L | 68-64 |
| NCAAB | 2022/02/22 01:00 | Eastern Illinois v SIU Edwardsville | W | 52-66 |
| NCAAB | 2022/02/19 22:00 | SIU Edwardsville v Belmont | L | 62-73 |
| NCAAB | 2022/02/18 01:30 | SIU Edwardsville v Tennessee State | L | 65-81 |
| NCAAB | 2022/02/12 21:30 | Tennessee Tech v SIU Edwardsville | W | 60-61 |
| NCAAB | 2022/02/11 01:30 | Tennessee Martin v SIU Edwardsville | W | 63-71 |
| NCAAB | 2022/03/04 18:00 | Illinois St v Northern Iowa | L | 65-78 |
| NCAAB | 2022/03/04 00:00 | Indiana State v Illinois St | W | 53-58 |
| NCAAB | 2022/02/26 21:00 | Indiana State v Illinois St | W | 66-86 |
| NCAAB | 2022/02/24 01:00 | Illinois St v Southern Illinois | L | 69-90 |
| NCAAB | 2022/02/22 01:00 | Loyola Chicago v Illinois St | L | 59-50 |
| NCAAB | 2022/02/19 19:00 | Illinois St v Bradley | L | 64-72 |
| NCAAB | 2022/02/16 01:00 | Northern Iowa v Illinois St | L | 72-70 |
| NCAAB | 2022/02/12 18:00 | Illinois St v Indiana State | L | 57-60 |