[5] Makedonikos 1-3 Larissa [4] 2022-08-29 20:45
Stadium: Gipedo Neas Efkarpias Makedonikou Round: 10
Home Manager: Georgios Amanatidis Away Manager: Giannis Taousianis
Home History
| Greece Play-Offs | 2022/06/11 14:30 | Pao Rouf v Makedonikos | D | 2-2 |
| Greece Play-Offs | 2022/06/01 14:00 | Makedonikos v Agrotikos Asteras | W | 1-0 |
| Greece Play-Offs | 2022/05/28 14:00 | Makedonikos v Ilioupoli | W | 2-1 |
| Greece Gamma Ethniki | 2022/05/22 14:00 | Iraklis Larisas v Makedonikos | D | 0-0 |
| Greece Play-Offs | 2022/05/18 14:00 | Proodeftiki v Makedonikos | D | 0-0 |
| Greece Play-Offs | 2022/05/15 14:00 | Makedonikos v Panachaiki | L | 0-1 |
| Greece Gamma Ethniki | 2022/04/06 13:00 | AE Lefkimmis v Makedonikos | L | 1-0 |
| Greece Gamma Ethniki | 2022/04/03 12:00 | Makedonikos v AEP Kozani | W | 1-0 |
Away History
| Greece Super League 2 | 2022/04/27 12:30 | PAOK Salonika B v Larissa | L | 2-0 |
| Greece Super League 2 | 2022/04/17 11:45 | Larissa v Olympiakos Volou | D | 0-0 |
| Greece Super League 2 | 2022/04/14 12:00 | Niki Volou v Larissa | D | 1-1 |
| Greece Super League 2 | 2022/04/10 11:45 | Larissa v Almopos Arideas | W | 2-1 |
| Greece Super League 2 | 2022/04/06 12:00 | Kavala v Larissa | W | 0-1 |
| Greece Super League 2 | 2022/04/03 14:00 | Larissa v Thesprotos | W | 1-0 |
| Greece Super League 2 | 2022/03/30 12:30 | Xanthi v Larissa | L | 2-0 |
| Greece Super League 2 | 2022/03/27 11:45 | Larissa v Pierikos | W | 1-0 |