[21] Krajicek/Sandgren 2-5 LA Kings [12] 2022-10-07 03:30
Stadium: Crypto.com Arena
Home Manager: Todd McLellan Away Manager: Don Granato
Head to Head
| NHL | 2022/03/06 18:00 | LA Kings v BUF Sabres | L | 3-0 |
| NHL | 2021/10/31 20:00 | BUF Sabres v LA Kings | L | 2-3 |
| NHL | 2019/12/21 18:00 | LA Kings v BUF Sabres | W | 2-3 |
| NHL | 2019/10/18 02:30 | BUF Sabres v LA Kings | W | 3-0 |
| NHL | 2018/12/12 00:00 | LA Kings v BUF Sabres | W | 3-4 |
| NHL | 2018/10/20 19:30 | BUF Sabres v LA Kings | W | 5-1 |
| NHL | 2018/02/17 18:00 | LA Kings v BUF Sabres | L | 4-2 |
| NHL | 2017/10/15 02:30 | BUF Sabres v LA Kings | L | 2-4 |
Home History
| NHL Pre-Season | 2022/10/04 23:00 | CAR Hurricanes v BUF Sabres | W | 2-4 |
| NHL Pre-Season | 2022/10/01 17:00 | PIT Penguins v BUF Sabres | W | 1-3 |
| NHL Pre-Season | 2022/09/28 23:00 | BUF Sabres v CLB Blue Jackets | L | 1-4 |
| NHL Pre-Season | 2022/09/27 23:00 | PHI Flyers v BUF Sabres | W | 1-2 |
| NHL Pre-Season | 2022/09/25 18:00 | BUF Sabres v WAS Capitals | W | 4-3 |
| NHL | 2022/04/29 23:00 | CHI Blackhawks v BUF Sabres | W | 2-3 |
| NHL | 2022/04/28 23:00 | BUF Sabres v BOS Bruins | L | 0-5 |
| NHL | 2022/04/23 16:30 | NY Islanders v BUF Sabres | W | 3-5 |
Away History
| NHL Pre-Season | 2022/10/07 01:00 | VGS Golden Knights v LA Kings | L | 6-4 |
| NHL Pre-Season | 2022/10/05 02:00 | LA Kings v ANA Ducks | L | 4-5 |
| NHL Pre-Season | 2022/10/03 01:00 | ANA Ducks v LA Kings | W | 1-2 |
| NHL Pre-Season | 2022/09/29 02:00 | SJ Sharks v LA Kings | L | 3-1 |
| NHL Pre-Season | 2022/09/27 02:00 | LA Kings v VGS Golden Knights | W | 2-1 |
| NHL Pre-Season | 2022/09/25 23:00 | LA Kings v SJ Sharks | L | 2-3 |
| NHL | 2022/05/15 02:00 | LA Kings v EDM Oilers | L | 0-2 |
| NHL | 2022/05/13 02:00 | EDM Oilers v LA Kings | L | 4-2 |