Head to Head
| Bolivia Clausura | 2022/09/04 19:00 | Guabira v Real Santa Cruz | L | 2-1 |
| Bolivia Apertura | 2022/04/21 22:15 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2022/02/13 19:00 | Real Santa Cruz v Guabira | D | 2-2 |
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | W | 3-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | L | 1-0 |
Home History
| Club Friendly List | 2023/01/23 20:00 | Libertad Gran Mamore FC v Real Santa Cruz | L | 2-0 |
| Bolivia Clausura | 2022/10/19 21:15 | The Strongest v Real Santa Cruz | L | 5-2 |
| Bolivia Clausura | 2022/10/16 21:15 | Real Santa Cruz v Always Ready | W | 1-0 |
| Bolivia Clausura | 2022/10/13 22:15 | Club Aurora v Real Santa Cruz | W | 1-2 |
| Bolivia Clausura | 2022/10/08 19:00 | Real Santa Cruz v Nacional Potosi | W | 2-1 |
| Bolivia Clausura | 2022/10/06 00:30 | Oriente Petrolero v Real Santa Cruz | L | 3-1 |
| Bolivia Clausura | 2022/09/30 19:00 | Real Santa Cruz v Real Tomayapo | D | 1-1 |
| Bolivia Clausura | 2022/09/16 19:00 | Atletico Palmaflor Vinto v Real Santa Cruz | L | 4-0 |
Away History
| Bolivia Clausura | 2022/10/20 00:30 | Guabira v Bolivar | W | 2-1 |
| Bolivia Clausura | 2022/10/15 23:30 | Royal Pari FC v Guabira | L | 3-2 |
| Bolivia Clausura | 2022/10/12 19:00 | Guabira v Universitario De Vinto | W | 1-0 |
| Bolivia Clausura | 2022/10/09 21:10 | Guabira v Oriente Petrolero | W | 2-1 |
| Bolivia Clausura | 2022/10/04 22:15 | Nacional Potosi v Guabira | L | 3-1 |
| Bolivia Clausura | 2022/10/01 00:00 | Guabira v Jorge Wilstermann | D | 1-1 |
| Bolivia Clausura | 2022/09/17 21:15 | Universitario de Sucre v Guabira | D | 1-1 |
| Bolivia Clausura | 2022/09/12 19:00 | Guabira v Club Aurora | D | 1-1 |