| Guatemala Liga Nacional Women | 2022/10/02 22:00 | Deportivo Mixco Women v Deportivo Amatitlan Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2022/09/25 17:00 | Suchitepequez (W) v Deportivo Mixco Women | L | 7-0 |
| Guatemala Liga Nacional Women | 2022/09/11 19:00 | Club Deportivo Xela Women v Deportivo Mixco Women | L | 5-1 |
| Guatemala Liga Nacional Women | 2022/05/29 16:00 | Antigua GFC (W) v Deportivo Mixco Women | L | 3-1 |
| Guatemala Liga Nacional Women | 2022/05/22 21:00 | Deportivo Mixco Women v Antigua GFC (W) | L | 1-3 |
| Guatemala Liga Nacional Women | 2022/04/25 00:00 | Deportivo Mixco Women v Tunecas Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2022/04/03 17:00 | Deportivo Mixco Women v K’iche FC Women | W | 1-0 |
| Guatemala Liga Nacional Women | 2022/03/27 21:00 | Antigua GFC (W) v Deportivo Mixco Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2022/11/13 18:00 | Club Deportivo Xela Women v Huehuetecas FC (W) | L | 1-0 |
| Guatemala Liga Nacional Women | 2022/10/23 17:11 | Deportivo Amatitlan Women v Huehuetecas FC (W) | W | 1-2 |
| Guatemala Liga Nacional Women | 2022/09/25 17:00 | Marquense Women v Huehuetecas FC (W) | L | 2-1 |
| Guatemala Liga Nacional Women | 2022/09/17 23:11 | Huehuetecas FC (W) v UNIFUT Antigua (W) | D | 1-1 |
| Guatemala Liga Nacional Women | 2022/08/20 21:00 | CSD Municipal (W) v Huehuetecas FC (W) | W | 1-2 |
| Guatemala Liga Nacional Women | 2022/04/24 19:00 | Club Deportivo Xela Women v Huehuetecas FC (W) | L | 4-0 |
| Guatemala Liga Nacional Women | 2022/04/03 20:00 | Suchitepequez (W) v Huehuetecas FC (W) | L | 4-2 |
| Guatemala Liga Nacional Women | 2022/02/27 01:30 | Huehuetecas FC (W) v Club Deportivo Xela Women | D | 0-0 |