[12] Independiente de Neuquen 30-13 Illinois [65] 2023-07-12 20:00
Stadium: Gies Memorial Stadium (Champaign, IL) Round: 1
Home Manager: James Franklin Away Manager: Bret Bielema
Head to Head
| NCAAF | 2021/10/23 16:00 | Illinois v Penn State | L | 20-18 |
| NCAAF | 2020/12/19 22:30 | Illinois v Penn State | W | 21-56 |
| NCAAF | 2018/09/22 01:00 | Penn State v Illinois | W | 63-24 |
| NCAAF | 2015/10/31 16:00 | Penn State v Illinois | W | 39-0 |
| NCAAF | 2014/11/22 17:00 | Illinois v Penn State | L | 16-14 |
| NCAAF | 2012/09/29 12:00 | Illinois v Penn State | W | 7-35 |
| NCAAF | 2011/10/29 12:00 | Penn State v Illinois | W | 10-7 |
| NCAAF | 2010/10/09 12:00 | Penn State v Illinois | L | 13-33 |
Home History
| NCAAF Bowl Games | 2023/01/02 22:00 | Utah v Penn State | W | 21-35 |
| NCAAF | 2022/11/26 21:00 | Michigan State v Penn State | W | 16-35 |
| NCAAF | 2022/11/19 20:30 | Penn State v Rutgers | W | 55-10 |
| NCAAF | 2022/11/12 20:30 | Maryland v Penn State | W | 0-30 |
| NCAAF | 2022/11/05 19:30 | Penn State v Indiana | W | 45-14 |
| NCAAF | 2022/10/29 16:00 | Ohio State v Penn State | L | 44-31 |
| NCAAF | 2022/10/22 23:30 | Minnesota v Penn State | W | 17-45 |
| NCAAF | 2022/10/15 16:00 | Penn State v Michigan | L | 17-41 |
Away History
| NCAAF Bowl Games | 2023/01/02 17:00 | Mississippi State v Illinois | L | 19-10 |
| NCAAF | 2022/11/26 20:30 | Illinois v Northwestern | W | 41-3 |
| NCAAF | 2022/11/19 17:00 | Illinois v Michigan | L | 17-19 |
| NCAAF | 2022/11/12 17:00 | Purdue v Illinois | L | 31-24 |
| NCAAF | 2022/11/05 19:30 | Illinois v Michigan State | L | 15-23 |
| NCAAF | 2022/11/05 19:30 | Michigan State v Illinois | L | 23-15 |
| NCAAF | 2022/10/29 19:30 | Illinois v Nebraska | W | 26-9 |
| NCAAF | 2022/10/15 16:00 | Minnesota v Illinois | W | 14-26 |