KC Chiefs 19-16 Tassamon Sangkawatana 2021-06-11 00:30
Stadium: Levi's Stadium
Home Manager: Kyle Shanahan Away Manager: Andy Reid
Head to Head
| NFL | 2020/02/02 23:30 | SF 49ers v KC Chiefs | W | 20-31 |
| NFL Preseason | 2019/08/25 00:00 | SF 49ers v KC Chiefs | L | 27-17 |
| NFL | 2018/09/23 17:00 | SF 49ers v KC Chiefs | W | 27-38 |
| NFL Preseason | 2017/08/12 01:00 | SF 49ers v KC Chiefs | L | 27-17 |
| NFL | 2014/10/05 20:25 | SF 49ers v KC Chiefs | L | 22-17 |