Stadium: Levi's Stadium Round: 15
Home Manager: Dan Quinn Away Manager: Kyle Shanahan
| 1 | 2 | H | 3 | 4 | F |
|---|---|---|---|---|---|
| 0 | 10 | 10 | 0 | 19 | 29 |
| 0 | 10 | 10 | 3 | 9 | 22 |
| ATL Falcons | SF 49ers |
| Lineup | |
|---|---|
| 73 - OT - Matt Gono | Mike McGlinchey - OT - 69 |
| 26 - Center back - Isaiah Oliver | Azeez Al-Shaair - Left back - 51 |
| 38 - Right back - Kenjon Barner | Sheldon Day - DT - 96 |
| 91 - OLB - Jacob Tuioti-Mariner | Ross Dwelley - TE - 82 |
| 94 - DT - Deadrin Senat | Mark Nzeocha - OLB - 53 |
| 28 - DB - Jordan Miller | Raheem Mostert - Right back - 31 |
| 20 - DB - Kendall Sheffield | Dontae Johnson - Center back - 35 |
| 87 - TE - Jaeden Graham | Kendrick Bourne - WR - 84 |
| 83 - WR - Russell Gage | Richie James - WR - 13 |
| 54 - MLB - Foyesade Oluokun | Marcell Harris - SAF - 36 |
| 76 - OT - Kaleb McGary | Tevin Coleman - Right back - 26 |
| 30 - Right back - Qadree Ollison | Laken Tomlinson - OG - 75 |
| 63 - OG - Chris Lindstrom | Emmanuel Moseley - Center back - 41 |
| 17 - WR - Olamide Zaccheaus | Daniel Helm - TE - 43 |
| 13 - WR - Christian Blake | DeForest Buckner - DT - 99 |
| 14 - WR - Justin Hardy | Jeremiah Valoaga - DE - 92 |
| 40 - FB - Keith Smith | Matt Breida - Right back - 22 |
| 99 - DE - Adrian Clayborn | Daniel Brunskill - OL - 60 |
| 37 - SAF - Ricardo Allen | Kentavius Street - DT - 95 |
| 24 - Right back - Devonta Freeman | Nick Mullens - QB - 4 |
| 36 - SAF - Kemal Ishmael | Elijah Lee - Left back - 47 |
| 70 - OT - Jake Matthews | Justin Skule - OT - 67 |
| 33 - Center back - Blidi Wreh-Wilson | Fred Warner - Left back - 54 |
| 47 - LS - Josh Harris | George Kittle - TE - 85 |
| 75 - OG - John Wetzel | Ahkello Witherspoon - Center back - 23 |
| 2 - QB - Matt Ryan | Solomon Thomas - DT - 94 |
| 9 - Pivot - Ryan Allen | Tarvarius Moore - DB - 33 |
| 95 - DT - Jack Crawford | Arik Armstead - DE - 91 |
| 80 - TE - Luke Stocker | Deebo Samuel - WR - 1 |
| 8 - QB - Matt Schaub | Kyle Nelson - LS - 86 |
| 51 - Center - Alex Mack | Dante Pettis - WR - 18 |
| 11 - WR - Julio Jones | Kyle Juszczyk - FB - 44 |
| 6 - K - Younghoe Koo | Levine Toilolo - TE - 83 |
| 35 - Left back - Jamal Carter | Dre Greenlaw - Left back - 57 |
| 23 - Right back - Brian Hill | D.J. Reed - Center back - 32 |
| 27 - SAF - Damontae Kazee | Mike Person - OG - 68 |
| 98 - DE - Takkarist McKinley | Jimmy Garoppolo - QB - 10 |
| 41 - SAF - Sharrod Neasman | Jeffery Wilson - Right back - 30 |
| 81 - TE - Austin Hooper | Jimmie Ward - DB - 20 |
| 59 - Left back - De'Vondre Campbell | Emmanuel Sanders - WR - 17 |
| 71 - OG - Wes Schweitzer | Robbie Gould - K - 9 |
| 45 - MLB - Deion Jones | Mitch Wishnowsky - Pivot - 3 |
| 97 - DT - Grady Jarrett | Joe Staley - OT - 74 |
| 96 - DT - Tyeler Davison | Nick Bosa - DE - 97 |
| 44 - OLB - Vic Beasley | Antone Exum - SS - 38 |
| 43 - Center back - Jamar Taylor | Ben Garland - OG - 63 |
| Substitutes | |