| 1 | 2 | H | 3 | 4 | F |
|---|---|---|---|---|---|
| 3 | 7 | 10 | 0 | 14 | 24 |
| 7 | 7 | 14 | 3 | 10 | 27 |
Lineups
| IND Colts | BUF Bills |
| Lineup | |
|---|---|
| 40 - Right back - Darius Anderson | Tremaine Edmunds - Left back - 49 |
| 49 - Left back - Matthew Adams | Dion Dawkins - OL - 73 |
| 59 - Left back - Jordan Glasgow | Tre'Davious White - Center back - 27 |
| 94 - DL - Tyquan Lewis | Justin Zimmer - DT - 61 |
| 28 - Right back - Jonathan Taylor | Dawson Knox - TE - 88 |
| 32 - SAF - Julian Blackmon | Ike Boettger - OL - |
| 45 - Left back - E.J. Speed | Darryl Johnson - DE - 92 |
| 16 - WR - Ashton Dulin | Quinton Jefferson - DL - |
| 97 - DL - Al-Quadin Muhammad | Reid Ferguson - LS - 69 |
| 11 - WR - Michael Pittman | Tyler Matakevich - Left back - 44 |
| 12 - WR - De'Michael Harris | Vernon Butler - DT - 94 |
| 37 - SAF - Khari Willis | Dean Marlowe - SAF - 31 |
| 63 - OL - Danny Pinter | Matt Milano - Left back - 58 |
| 57 - DL - Kemoko Turay | Isaiah McKenzie - WR - 19 |
| 3 - K - Rodrigo Blankenship | Ed Oliver - DT - 91 |
| 44 - Left back - Zaire Franklin | Josh Allen - QB - 17 |
| 72 - OL - Braden Smith | Corey Bojorquez - Pivot - 9 |
| 34 - Center back - Isaiah Rodgers | Devin Singletary - Right back - 26 |
| 95 - DL - Taylor Stallworth | Ryan Bates - OL - 71 |
| 99 - DL - DeForest Buckner | Levi Wallace - DB - 39 |
| 7 - QB - Jacoby Brissett | Andre Smith - Left back - 9 |
| 80 - WR - Trey Burton | Reggie Gilliam - TE - 41 |
| 75 - OL - Chaz Green | Siran Neal - Center back - 33 |
| 64 - OL - Mark Glowinski | Taron Johnson - Center back - 7 |
| 38 - Center back - T.J. Carrie | Harrison Phillips - DT - 99 |
| 84 - TE - Jack Doyle | Jaquan Johnson - DB - 46 |
| 31 - DB - Tavon Wilson | Stefon Diggs - WR - 14 |
| 65 - OT - Jared Veldheer | Daryl Williams - T - 75 |
| 17 - QB - Philip Rivers | Mario Addison - DE - 97 |
| 50 - Left back - Justin Houston | Taiwan Jones - Right back - 25 |
| - DL - Denico Autry | Andre Roberts - WR - |
| 27 - Center back - Xavier Rhodes | Tyler Bass - K - 2 |
| 78 - OL - Ryan Kelly | Lee Smith - TE - 85 |
| 46 - Left back - Luke Rhodes | Micah Hyde - Center back - 23 |
| - Center - Joey Hunt | John Brown - WR - |
| 53 - Left back - Darius Leonard | Jerry Hughes - DE - 55 |
| 58 - Left back - Bobby Okereke | Jordan Poyer - Center back - 21 |
| 21 - Right back - Nyheim Hines | Josh Norman - Center back - 29 |
| 56 - OL - Quenton Nelson | Gabriel Davis - WR - 13 |
| 30 - OLB - George Odum | Matt Barkley - QB - 5 |
| 35 - Center back - Tremon Smith | Zack Moss - Right back - 20 |
| 23 - Center back - Kenny Moore II | Ty Nsekhe - OT - 77 |
| 8 - Pivot - Rigoberto Sanchez | Jon Feliciano - OL - 76 |
| 14 - WR - Zach Pascal | Brian Winters - OL - |
| 54 - Left back - Anthony Walker | Mitch Morse - OL - 60 |
| 90 - DT - Grover Stewart | A.J. Epenesa - DE - 57 |
| 81 - TE - Mo Alie-Cox | Cole Beasley - WR - |
| 13 - WR - TY Hilton | A.J. Klein - Left back - 54 |
| Substitutes | |
Events
- 1st Drive - First Down - Yes #IND Colts #Q1#10'#249#15
- 1st Drive - Punt #IND Colts #Q1#10'#249#15
- 2nd Drive - First Down - No #BUF Bills #Q1#9'#347#15
- 2nd Drive - Punt #BUF Bills #Q1#9'#347#15
- 3rd Drive - First Down - Yes #IND Colts #Q1#5'#576#15
- 3rd Drive - Field Goal Attempt #IND Colts #Q1#5'#576#15
- 1st Score - Field Goal - #IND Colts #Q1#5'#576#15
- 2nd Score - Touchdown - Knox #BUF Bills #Q1#1'#793#15
- 1st Quarter Race to 6 - #BUF Bills #Q1#1'#793#15
- 4th Drive - First Down - Yes #BUF Bills #Q1#1'#793#15
- 4th Drive - Offensive Touch Down - #BUF Bills #Q1#1'#793#15
- 1 PAT - #BUF Bills #Q1#1'#793#15
- 5th Drive - First Down - Yes #IND Colts #Q1#0'#889#15
- 5th Drive - Punt #IND Colts #Q1#0'#889#15
- Score After 1st Quarter - 3-7
- 6th Drive - First Down - No #BUF Bills #Q2#13'#96#15
- 6th Drive - Punt #BUF Bills #Q2#13'#96#15
- 3rd Score - Touchdown - Taylor #IND Colts #Q2#8'#413#15
- 2nd Quarter Race to 6 - #IND Colts #Q2#8'#413#15
- 7th Drive - First Down - Yes #IND Colts #Q2#8'#413#15
- 7th Drive - Offensive Touch Down - #IND Colts #Q2#8'#413#15
- 1 PAT - #IND Colts #Q2#8'#413#15
- Race to 10 - #IND Colts #Q2#8'#413#15
- 8th Drive - First Down - No #BUF Bills #Q2#6'#533#15
- 8th Drive - Punt #BUF Bills #Q2#6'#533#15
- 9th Drive - First Down - Yes #IND Colts #Q2#1'#795#15
- 9th Drive - Turnover #IND Colts #Q2#1'#795#15
- 4th Score - Touchdown - Allen #BUF Bills #Q2#0'#883#15
- 10th Drive - First Down - Yes #BUF Bills #Q2#0'#883#15
- 10th Drive - Offensive Touch Down - #BUF Bills #Q2#0'#883#15
- 1 PAT - #BUF Bills #Q2#0'#883#15
- Score After 2nd Quarter - 10-14
- 12th Drive - First Down - Yes #BUF Bills #Q3#11'#240#15
- 12th Drive - Field Goal Attempt #BUF Bills #Q3#11'#240#15
- 5th Score - Field Goal - #BUF Bills #Q3#11'#240#15
- Race to 15 - #BUF Bills #Q3#11'#240#15
- 13th Drive - First Down - Yes #IND Colts #Q3#3'#680#15
- 13th Drive - Field Goal Attempt #IND Colts #Q3#3'#680#15
- Score After 3rd Quarter - 10-17
- 6th Score - Touchdown - Diggs #BUF Bills #Q4#13'#62#15
- 4th Quarter Race to 6 - #BUF Bills #Q4#13'#62#15
- Race to 20 - #BUF Bills #Q4#13'#62#15
- 14th Drive - First Down - Yes #BUF Bills #Q4#13'#62#15
- 14th Drive - Offensive Touch Down - #BUF Bills #Q4#13'#62#15
- 1 PAT - #BUF Bills #Q4#13'#62#15
- 7th Score - Touchdown - Pascal #IND Colts #Q4#11'#207#15
- 15th Drive - First Down - Yes #IND Colts #Q4#11'#207#15
- 15th Drive - Offensive Touch Down - #IND Colts #Q4#11'#207#15
- 16th Drive - First Down - Yes #BUF Bills #Q4#8'#418#15
- 16th Drive - Field Goal Attempt #BUF Bills #Q4#8'#418#15
- 8th Score - Field Goal - #BUF Bills #Q4#8'#418#15
- 4th Quarter Race to 9 - #BUF Bills #Q4#8'#418#15
- Race to 25 - #BUF Bills #Q4#8'#418#15
- 9th Score - Touchdown - Doyle #IND Colts #Q4#5'#542#15
- 4th Quarter Race to 12 - #IND Colts #Q4#5'#542#15
- 17th Drive - First Down - Yes #IND Colts #Q4#5'#542#15
- 17th Drive - Offensive Touch Down - #IND Colts #Q4#5'#542#15
- 2 PAT - #IND Colts #Q4#5'#542#15
- 18th Drive - First Down - Yes #BUF Bills #Q4#2'#735#15
- 18th Drive - Punt #BUF Bills #Q4#2'#735#15