Head to Head
| England Premier League 2 | 2024/11/29 14:00 | Stoke U21 v Southampton U21 | L | 0-3 |
| England Premier League 2 | 2024/03/08 19:00 | Southampton U21 v Stoke U21 | L | 5-1 |
| England Premier League 2 | 2023/04/14 18:00 | Southampton U21 v Stoke U21 | L | 2-0 |
| England Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | L | 0-3 |
Home History
| England U21 Premier League Cup | 2025/11/30 14:00 | Stoke U21 v Bristol City U21 | W | 3-2 |
| England U21 Premier League Cup | 2025/11/21 19:00 | Derby U21 v Stoke U21 | D | 2-2 |
| England Premier League 2 | 2025/11/07 12:00 | Crystal Palace U21 v Stoke U21 | D | 2-2 |
| England Premier League 2 | 2025/11/02 13:00 | Stoke U21 v West Brom U21 | D | 1-1 |
| England U21 Premier League Cup | 2025/10/28 19:00 | Stoke U21 v Sheff Utd U21 | L | 1-2 |
| England Premier League 2 | 2025/10/25 11:30 | Sunderland U21 v Stoke U21 | W | 1-2 |
| England Premier League 2 | 2025/10/03 18:00 | Stoke U21 v Blackburn U21 | W | 3-1 |
| England Premier League 2 | 2025/09/27 10:00 | Chelsea U21 v Stoke U21 | W | 1-2 |
Away History
| Premier League International Cup | 2025/12/02 19:00 | Southampton U21 v Monaco U21 | L | 0-2 |
| England National League Cup | 2025/11/25 19:00 | Sutton Utd v Southampton U21 | L | 4-1 |
| England Premier League 2 | 2025/11/07 19:00 | Southampton U21 v Arsenal U21 | D | 1-1 |
| England Premier League 2 | 2025/11/01 13:30 | Tottenham U21 v Southampton U21 | W | 1-2 |
| Premier League International Cup | 2025/10/29 19:00 | Southampton U21 v Real Madrid U21 | D | 1-1 |
| England Premier League 2 | 2025/10/25 12:00 | Leicester U21 v Southampton U21 | L | 3-1 |
| England National League Cup | 2025/10/21 18:00 | Aldershot v Southampton U21 | W | 5-7 |
| England Premier League 2 | 2025/10/03 18:00 | Southampton U21 v Derby U21 | W | 4-1 |