[29] DET Red Wings 1-3 BUF Sabres [16] 2018-11-27 04:00
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: Jeff Blashill
Head to Head
| NHL | 2018/11/25 00:00 | BUF Sabres v DET Red Wings | L | 3-2 |
| NHL | 2018/03/29 23:00 | DET Red Wings v BUF Sabres | W | 6-3 |
| NHL | 2018/02/23 00:30 | BUF Sabres v DET Red Wings | L | 3-2 |
| NHL | 2017/11/18 00:30 | BUF Sabres v DET Red Wings | W | 1-3 |
| NHL | 2017/10/24 23:30 | BUF Sabres v DET Red Wings | L | 1-0 |
| NHL | 2017/03/20 23:30 | BUF Sabres v DET Red Wings | L | 2-1 |
| NHL | 2017/01/21 00:00 | DET Red Wings v BUF Sabres | L | 2-3 |
| NHL | 2016/12/28 00:30 | BUF Sabres v DET Red Wings | L | 4-3 |
Home History
| NHL | 2018/11/27 00:30 | CLB Blue Jackets v DET Red Wings | L | 7-5 |
| NHL | 2018/11/25 00:00 | BUF Sabres v DET Red Wings | L | 3-2 |
| NHL | 2018/11/23 21:00 | DET Red Wings v WAS Capitals | L | 1-3 |
| NHL | 2018/11/22 00:30 | BOS Bruins v DET Red Wings | W | 2-3 |
| NHL | 2018/11/17 18:00 | DET Red Wings v NJ Devils | W | 3-2 |
| NHL | 2018/11/16 00:30 | DET Red Wings v OTT Senators | L | 1-2 |
| NHL | 2018/11/14 00:30 | ARZ Coyotes v DET Red Wings | W | 1-6 |
| NHL | 2018/11/11 00:00 | DET Red Wings v CAR Hurricanes | W | 4-3 |
Away History
| NHL | 2018/11/25 00:00 | BUF Sabres v DET Red Wings | W | 3-2 |
| NHL | 2018/11/23 21:00 | MTL Canadiens v BUF Sabres | W | 2-3 |
| NHL | 2018/11/22 00:30 | PHI Flyers v BUF Sabres | W | 2-5 |
| NHL | 2018/11/20 00:00 | BUF Sabres v PIT Penguins | W | 5-4 |
| NHL | 2018/11/17 23:00 | BUF Sabres v MIN Wild | W | 3-2 |
| NHL | 2018/11/17 01:00 | BUF Sabres v WPG Jets | W | 2-1 |
| NHL | 2018/11/14 00:30 | TB Lightning v BUF Sabres | W | 1-2 |
| NHL | 2018/11/10 18:00 | VAN Canucks v BUF Sabres | W | 3-4 |