Southern Illinois 48-28 South Dakota 2019-06-02 05:00
Stadium: DakotaDome Round: 1
Home Manager: Nick Hill Away Manager: Bob Nielson
Head to Head
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
| NCAAF | 2017/10/28 20:00 | South Dakota v SO Illinois | L | 42-0 |
Home History
| NCAAF FCS | 2018/11/17 20:30 | SO Illinois v North Dakota State | L | 17-65 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | L | 57-38 |
| NCAAF FCS | 2018/11/03 18:00 | Western Illinois v SO Illinois | L | 34-31 |
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | W | 35-49 |
| NCAAF | 2018/10/20 19:00 | SO Illinois v Indiana State | L | 21-24 |
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | L | 3-51 |
| NCAAF | 2018/10/06 22:00 | SO Illinois v Youngstown State | L | 14-17 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
Away History
| NCAAF FCS | 2018/11/17 20:00 | South Dakota v South Dakota State | L | 27-49 |
| NCAAF FCS | 2018/11/10 19:00 | Western Illinois v South Dakota | W | 12-17 |
| NCAAF FCS | 2018/11/03 17:00 | South Dakota v Indiana State | L | 48-51 |
| NCAAF | 2018/10/27 19:00 | South Dakota v North Dakota State | L | 14-59 |
| NCAAF | 2018/10/20 22:00 | Youngstown State v South Dakota | L | 29-17 |
| NCAAF | 2018/10/13 23:00 | Northern Iowa v South Dakota | L | 42-28 |
| NCAAF | 2018/10/06 19:00 | Missouri St v South Dakota | W | 28-35 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | W | 31-24 |