Head to Head
| NCAAF | 2005/09/24 12:00 | South Florida v Louisville | L | 45-14 |
| NCAAF | 2004/10/22 12:00 | Louisville v South Florida | W | 41-9 |
| NCAAF | 2003/10/04 12:00 | South Florida v Louisville | L | 31-28 |
Home History
| NCAAF Bowl Games | 2006/01/02 12:00 | Louisville v Virginia Tech | L | 24-35 |
| NCAAF | 2005/12/03 12:00 | Connecticut v Louisville | W | 20-30 |
| NCAAF | 2005/11/26 12:00 | Louisville v Syracuse | W | 41-17 |
| NCAAF | 2005/11/11 12:00 | Louisville v Rutgers | W | 56-5 |
| NCAAF | 2005/11/03 12:00 | Louisville v Pittsburgh | W | 42-20 |
| NCAAF | 2005/10/22 12:00 | Cincinnati v Louisville | W | 22-46 |
| NCAAF | 2005/10/15 12:00 | West Virginia v Louisville | L | 46-44 |
| NCAAF | 2005/10/08 12:00 | Louisville v North Carolina | W | 69-14 |
Away History
| NCAAF Bowl Games | 2005/12/31 12:00 | NC State v South Florida | L | 14-0 |
| NCAAF | 2005/12/03 12:00 | South Florida v West Virginia | L | 13-28 |
| NCAAF | 2005/11/26 12:00 | Connecticut v South Florida | L | 15-10 |
| NCAAF | 2005/11/19 12:00 | South Florida v Cincinnati | W | 31-16 |
| NCAAF | 2005/11/12 12:00 | Syracuse v South Florida | W | 0-27 |
| NCAAF | 2005/11/05 12:00 | Rutgers v South Florida | W | 31-45 |
| NCAAF | 2005/10/15 12:00 | Pittsburgh v South Florida | L | 31-17 |
| NCAAF | 2005/10/01 12:00 | Miami Florida v South Florida | L | 27-7 |