Home History
| NCAAF | 2010/11/27 12:00 | Wisconsin v Northwestern | L | 70-23 |
| NCAAF | 2010/11/20 12:00 | Northwestern v Illinois | L | 27-48 |
| NCAAF | 2010/11/13 12:00 | Northwestern v Iowa | W | 21-17 |
| NCAAF | 2010/11/06 12:00 | Penn State v Northwestern | L | 35-21 |
| NCAAF | 2010/10/30 12:00 | Indiana v Northwestern | W | 17-20 |
| NCAAF | 2010/10/23 12:00 | Northwestern v Michigan State | L | 27-35 |
| NCAAF | 2010/10/09 12:00 | Northwestern v Purdue | L | 17-20 |
| NCAAF | 2010/10/02 12:00 | Minnesota v Northwestern | W | 28-29 |
Away History
| NCAAF | 2010/11/27 12:00 | Rice v UAB | W | 28-23 |
| NCAAF | 2010/11/20 12:00 | Rice v East Carolina | W | 62-38 |
| NCAAF | 2010/11/13 12:00 | Tulane v Rice | L | 54-49 |
| NCAAF | 2010/11/06 12:00 | Tulsa v Rice | L | 64-27 |
| NCAAF | 2010/10/23 12:00 | Central Florida v Rice | L | 41-14 |
| NCAAF | 2010/10/16 12:00 | Rice v Houston | W | 34-31 |
| NCAAF | 2010/10/09 12:00 | UTEP v Rice | L | 44-24 |
| NCAAF | 2010/10/02 12:00 | Rice v SMU | L | 31-42 |