Stadium: Travis E. Parker Field at Horace L. McCool Stadium Round: 1
| NCAAF | 2018/11/10 20:00 | Delta State v Mississippi College Choctaws | W | 28-21 |
| NCAAF | 2018/11/03 18:00 | West Georgia v Delta State | L | 29-17 |
| NCAAF | 2018/10/25 23:00 | Delta State v Shorter | W | 46-20 |
| NCAAF | 2018/10/13 19:00 | West Alabama Tigers v Delta State | L | 17-14 |
| NCAAF | 2018/10/06 17:00 | Valdosta State v Delta State | L | 59-28 |
| NCAAF | 2018/09/29 23:00 | Delta State v West Florida | L | 21-30 |
| NCAAF | 2018/09/22 23:00 | Delta State v North Greenville Crusaders | L | 20-33 |
| NCAAF | 2018/09/15 23:00 | Florida Tech Panthers v Delta State | L | 30-12 |
| NCAAF | 2018/11/10 20:00 | Wingate Bulldogs v Tusculum Pioneers | L | 16-12 |
| NCAAF | 2018/11/03 17:30 | VMI v Tusculum Pioneers | L | 20-11 |
| NCAAF | 2018/10/27 17:30 | Tusculum Pioneers v Carson–Newman Eagles | W | 41-28 |
| NCAAF | 2018/10/20 17:30 | Catawba College v Tusculum Pioneers | L | 55-37 |
| NCAAF | 2018/10/13 19:00 | Tusculum Pioneers v Newberry Wolves | W | 14-0 |
| NCAAF | 2018/10/06 17:30 | Mars Hill Lions v Tusculum Pioneers | W | 28-31 |
| NCAAF | 2018/09/29 22:00 | Lenoir Rhyne Bears v Tusculum Pioneers | L | 35-10 |
| NCAAF | 2018/09/14 23:00 | Tusculum Pioneers v Limestone Saints | W | 37-10 |