Stadium: Jack Britt Memorial Stadium Round: 1
| NCAAF | 2018/11/10 17:00 | Lake Erie v Ohio Dominican Panthers | L | 6-62 |
| NCAAF | 2018/11/03 16:00 | Thomas More v Lake Erie | L | 44-0 |
| NCAAF | 2018/10/27 16:00 | Lake Erie v Tiffin Dragons | L | 28-40 |
| NCAAF | 2018/10/20 18:00 | Kentucky Wesleyan v Lake Erie | L | 46-6 |
| NCAAF | 2018/10/13 23:00 | Lake Erie v Walsh U. Cavaliers | L | 0-29 |
| NCAAF | 2018/10/06 17:30 | Alderson Broaddus Battlers v Lake Erie | L | 55-27 |
| NCAAF | 2018/09/29 16:00 | Lake Erie v Findlay Oilers | L | 7-70 |
| NCAAF | 2018/09/22 20:00 | Hillsdale Chargers v Lake Erie | L | 41-7 |
| NCAAF | 2018/11/10 17:00 | Alderson Broaddus Battlers v Kentucky Wesleyan | L | 51-7 |
| NCAAF | 2018/11/03 16:00 | Ohio Dominican Panthers v Kentucky Wesleyan | L | 65-7 |
| NCAAF | 2018/10/27 17:00 | Hillsdale Chargers v Kentucky Wesleyan | L | 34-0 |
| NCAAF | 2018/10/20 18:00 | Kentucky Wesleyan v Lake Erie | W | 46-6 |
| NCAAF | 2018/10/13 20:00 | Tiffin Dragons v Kentucky Wesleyan | L | 43-17 |
| NCAAF | 2018/09/29 18:00 | Kentucky Wesleyan v Walsh U. Cavaliers | L | 17-23 |
| NCAAF | 2018/09/22 18:00 | Kentucky Wesleyan v Malone University Pioneers | W | 44-38 |
| NCAAF | 2018/09/15 23:00 | Kentucky Wesleyan v Kentucky Thorobreds | W | 19-13 |